New Drug Could Be A 'Game-Changer' In Fight Against Obesity: UK Study The drug, semaglutide, works by hijacking the body’s own appetite-regulating system in the brain leading to reduced hunger and calorie intake. AP Outlook Web Bureau 2021-02-11T22:46:49+05:30 New Drug Could Be A 'Game-Changer' In Fight Against Obesity: UK Study outlookindia.com 2021-02-11T22:50:56+05:30 The results of trials of a new drug have given new hopes to combat obesity successfully. The findings from a large-scale international trial are being hailed as a “game-changer” in the UK for improving the health of people with obesity. The drug could even play a major part in helping reduce the impact of diseases such as COVID-19.