New PTSD Biotypes Enable Improved Tests by Colleen Fleiss on January 24, 2021 at 11:26 PM New and distinct biotypes for post-traumatic stress disorder, the first of their kind for any psychological disorder have been discovered by PTSD Systems Biology Consortium, led by scientists from the Walter Reed Army Institute of Research. Publishing their work in Molecular Psychiatry in a manuscript first authored by WRAIR's Dr. Ruoting Yang, researchers used blood tests from male, combat-exposed veterans across a three year period to identify two PTSD biotypes, G1--characterized by mild, inherent co-morbidities typical of PTSD--and G2--which includes more severe symptoms typical of PTSD and report more physical distress--with differing genetic markers and underlying mechanisms of disease.