Product News: Easy-to-use reversed-phase capillary columns and emitters improve high-resolution LC-MS analysis 25 Feb 2021 Proteomics, clinical peptides, and biopharmaceutical research laboratories performing high throughput, high-performance liquid chromatography (HPLC), or liquid chromatography-mass spectrometry (LC-MS) analysis can now benefit from novel capillary chromatography columns and nano- and capillary emitters, specifically designed for highly sensitive top-down, middle-down analysis. These columns and emitters enable laboratories to achieve high-resolution, low-flow separations for intact proteins, monoclonal antibodies (mAbs) and peptides. The Thermo Scientific MAbPac Reversed-Phase (RP) Capillary HPLC Column builds upon the separation power and reliability of the proven MAbPac RP chemistry in analytical flow. Together with the new Thermo Scientific EASY-Spray Nano and Capillary Emitters, the temperature-controlled MAbPac column enables maximum reliability and performance, while also providing excellent resolution, long column lifetime and low carry-over. The capillary format of the LC column improves sensitivity, achieving outstanding data results even with smaller sample volumes. The format makes the versatile column ideal for applications such as peptide mapping characterization and analysis of mAbs fragments, antibody drug conjugates (ADC) and PEGylated proteins.