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Colistin and carbapenems are two categories of antibiotics utilized as a last-resort treatment for infections caused by multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria. Resistance to these last lines of defence can eventuate total antibiotic resistance. At present, there is scarcity of research present to estimate the current load and impact of the residual concentrations of colistin and carbapenems on environmental microbiome. However, there have been several reports demonstrating resistance development to colistin and carbapenems in a range of environmental compartme...

High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the pharmaceutical industry due to its high throughput, sensitivity, and selectivity.

SPOT ON path to fast MS analysis, addressing challenges faced by analytical testing laboratories.

Christopher Hudalla of ProVerde Laboratories Inc. discussed how using liquid chromatography–mass spectrometry (LC–MS) could be used to quantify specific classes of PPL constituents that can help streamline cannabis extraction.

In this application note, Shimadzu Corporation introduces three analytical instruments to evaluate infectious diseases caused by harmful microorganisms: liquid chromatography-mass spectrometer (LC-MS), matrix assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS), and gas chromatography-mass spectrometer (GC-MS). The note highlights the rise of bacterial infectious diseases in the past 10 years, emphasizing the importance of investigating and examining these infecti