For a decade, the ethos of the University of Pretoria (UP) Institute for Sustainable Malaria Control (UP ISMC) has been to transcend disciplines to allow for transdisciplinary collaborations and translational applications towards malaria elimination, as outlined in a paper published in In order for research to make an impact on the drive towards malaria elimination, researchers must collaborate in a transdisciplinary manner and ensure that their research translates into tangible outcomes to save lives. But the disease is not making things easy. Despite significant reductions in the global malaria burden since the upscaling of control strategies in the early 2000s, the disease remains a major public health concern.