Helicobacter pylori ( H. pylori) infected patients with a probiotic therapy in addition to an eradication regimen reduced symptoms of distension and abdominal pain compared to patients who received the eradication regimen plus placebo, a small randomized trial in Spain found. Among 80 patients receiving bismuth-containing quadruple eradication therapy, abdominal pain symptoms decreased in 42% of those given the probiotic ( Lactobacillus reuteri) versus 19% with placebo (OR 0.27, CI 0.13-0.58, P