email article Psoriasis continues to be the second largest contributor to skin-related disability globally, and its prevalence continues to increase. This chronic, disfiguring disease can have a significant negative impact on quality of life, especially in patients with a low socioeconomic status. In its 2016 Global Report on Psoriasis, the World Health Organization (WHO) noted that psoriasis is estimated to affect at least 100 million adults and children worldwide, and that "many people suffer needlessly" due to missed or delayed diagnosis, poor access to care, inadequate treatment, and social stigmatization. To better understand the global incidence, prevalence, and disease burden associated with psoriasis, investigators analyzed trends from 1990 to 2017 in 195 countries using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). The authors found a positive linear relationship between the prevalence of psoriasis and associated comorbidities including cardiovascular disease, type 2 diabetes, stroke, non-Hodgkin and Hodgkin lymphoma, nonmelanoma skin cancer, and inflammatory bowel disease. The male-to-female ratio was similar across all ages with a peak between 60 and 70 years but notably psoriasis burden was greatest in countries with high income and sociodemographic index.