More indictments have been issued in the drug-trafficking case known as "Prison Empire" by the South Carolina State Grand Jury, making it the largest number of defendants for a single narcotics conspiracy investigation in South Carolina's courts, according to the state Attorney General's Office. The indictments collectively contain 487 charges alleged within 297 counts against 100 defendants, according to a press release from the Attorney General. And there is a connection to a federal case where a web of organized crime allegedly operated in prisons with gangs, drugs and murder. That case has been described as the largest federal racketeering conspiracy in South Carolina history.