email article Neither fish oil nor vitamin D supplementation worked in the long-term primary prevention of atrial fibrillation (Afib), according to the VITAL Rhythm study. Adults showed no reduction in incident Afib over a median 5.3 years of daily treatment with omega-3 fatty acids (3.7% vs 3.4% with olive oil placebo, HR 1.09, 95% CI 0.96-1.24) or vitamin D 3 supplementation (3.7% vs 3.4% with soybean oil placebo, HR 1.09, 95% CI 0.96-1.25), reported Christine Albert, MD, MPH, of Cedars-Sinai Medical Center in Los Angeles, and colleagues. There was no interaction between the two treatments in the 2×2 factorial randomized trial. Results remained nonsignificant when individuals were censored for nonadherence, they stated in