March 15, 2021 Older people who’ve had an MI without any clinical symptoms appear to be at risk for subsequent ischemic strokes, according to an analysis of the Cardiovascular Health Study. Over roughly a decade of follow-up, people who had a silent MI were a relative 47% more likely to have an ischemic stroke after accounting for demographics and vascular risk factors (HR 1.47; 95% CI 1.01-2.16), Alexander Merkler, MD (NewYork-Presbyterian and Weill Cornell Medicine, New York, NY), reported as part of the virtual International Stroke Conference 2021, which begins later this week. When the results were broken down by stroke subtype, the relationship remained significant for nonlacunar strokes (HR 2.18; 95% CI 1.24-3.83) but not for lacunar or other/unknown strokes.