applause i want the truth. laughter stephen you cant handle the tru gags applause and scene. cheers and applause john krasinski, 13 hours opens nationwide on january 13. Well be right back. P proof of less joint pain. And clearer skin. This is my body of proof that i can fight Psoriatic Arthritis humira works by targeting and helping to block a specific source of inflammation that contributes to both joint and skin symptoms. Its proven to stop further joint damage and clear skin in many adults. Doctors have been prescribing humira for 10 years. Humira can lower your ability to fight infections, including tuberculosis. Serious, sometimes fatal infections and cancers, including lymphoma, have happened, as have blood, liver and nervous system problems, serious allergic reactions, and new or worsening heart failure. Before treatment, get tested for tb. Tell your doctor if youve been to areas where certain fungal infections are common, and if youve had tb, hepatitis b, are prone to infections, or have flulike symptoms or sores. Dont start humira if you have an infection. Want more proof . About humira. Humira. This is my body of proof plumpify your lashes a ginormous lasht lifting brush boosts lashes to 50 times the volume and lifts lashest up up and away new plumpify mascara from easy breezy ive smoked a lot and quit a lot, but ended up nowhere. Now i use this. The nicoderm cq patch, with unique extended release technology, helps prevent the urge to smoke all day. I want this time to be my last time. Thats why i choose nicoderm cq. Fact. Advil pain relievers are to treat their aches and pains more people reach for advil. Relief doesnt get any better than this. Advil. Southwest has officially been in denver for ten years. We couldnt be happier to be here or more excited about the years to come. To celebrate, we got you 56 nonstop destinations. Because as everybody knows, the tenyear anniversary is the nonstop destination amazing years, denver. What can we say . We like you back. sfx clap, clap, ding sandwich. With all white breast meat and no artificial preservatives, its hard to resist. You ate all the turkey for our rhode island market how am i supposed to do Quality Control if i cant eat the product . You work in accounting. The tender turkey breast sandwich, cheers and applause stephen welcome back, everybody. I hope everyone out there had a Great Holiday season. I dont know how you spent it, but statistically speaking, it was probably watching star wars, because over the last couple weeks, millions of people went to see the force awakens, pushing its box office past titanic. Sorry, jack. You died for nothing. laughter the force awakens has a 93 certified fresh rating on rotten tomatoes. But im a catholic, so i get all my Movie Reviews from Losservatore Romano, the official newspaper of the vatican. Thats right, they have a newspaper. Some stories are just too complicated to report through colored smoke. And Losservatore Romano was not impressed. Just look at their headline insulting or very delicious. Ill have the veal sfocato, suffice to say, these guys and i assume theyre guys were not confused and hazy, even adding that the blockbuster overdoes the darkness. The vatican and this is true gave a better review to spotlight. Im not joking. They were especially disappointed in the force awakens villains, saying they fail most spectacularly in counterpart of darth vader, kylo ren, wears a mask merely to i didnt have a problem with the mask, but i was upset that, when he took it off, his hair was somehow perfectly fluffed. laughter how is that possible . Dark side, sign me up but i have to say, this review has me really torn. Im caught in a crisis of faith between deeply held beliefs embedded in me since childhood and the Catholic Church. laughter applause so, before applause thats all right. You can applaud. You can applaud. So before you jump on them for not enjoying star wars as much as we did, let me defend my church by explaining why they might have issues with it. For one thing, its the story of a savior, born in the desert, chosen to redeem mankind. Thats copyright infringement. laughter you think god is vengeful . You should meet his lawyer, ira. Now, it doesnt help that the original trilogy featured a father, a son, and a holy ghost. The Catholic Church might take issue with a bad guy who spends the entire movie trying to stab people with a cross. Wars and the Catholic Church have large followings of virgins. applause so get off their back. Well be right back with killer mike. Upon. Whats this . A box. It takes worn out things and makes them better. Its our biggest breakthrough yet. Were taking worn out batteries and making them into something strong. Energizer ecoadvanced. P worlds first long lasting r battery made with r 4 recycled batteries. Starin at it by malibu n helene stand out. By design. cheers and applause stephen welcome. Ladies and gentlemen, my next guest is one of the biggest names in hiphop, a civic leader, and an activist. Please welcome killer mike. cheers and applause killer mike thanks for being here. Thank you. My wife put me on a diet, i lost four pounds and now i cant keep my pants up. Stephen thank you for wearing your formal sweats for us tonight. Actually, these are formal. This is my p. T. A. Meeting outfit. Stephen oh, really, when you have to go talk . Exactly, when i have to go talk around other parents and you dont want to dress like, you know, a rapper. You put on a sweat suit that has a cardigan sweater. Stephen when you go meet your kids in elementary school, do the teachers go, now, killer they say that after we discuss why my child is fighting. laughter stephen could it have anything to do with your name, killer mike . Its the girls that are fighting. The boys are pretty good. Stephen girls can fight. Its a whole new world. Yeah. Stephen why killer mike . I didnt name myself. I want to say it wasnt like some kid was standing in the mirror and decide he look like aid killer. I would have like bike bougati mike, or ferrari mike. I rapid as a kid and rapped really well and seven or eight other guys and stood on a desk and said, that kids a killer. And after that nobody ever called me skunk again in my life, just killer. Stephen killer, thats awesome. Your original name is michael render. Michael render is my name. Stephen thats a good name, too, mike render. Like youre tearing the mike apart. And my daughters name is michael render. Stephen your daughters thats a pretty name for a girl. I think so. Shes got to stop fighting. Stephen we all have to stop fighting. We all have to stop fighting. Yes. Stephen as i said youre a civic leader. Youre socially active. I am. Stephen hiphop artist. I own barber shops. Stephen you do own barber shops. Im part of a very good rap group called run the jewels. Were working on part three right now. Stephen it was Just Announced you guys are going to be included in coachella this year, right . Back to back. Stephen thats fantastic. We are back. Stephen this year, if i can speak for all white people, laughter i prefer you speaking for all white people. Stephen another you speak for all black people, okay . Today i do. Stephen okay. This year, tragically, a lot of people in the White Community have found out about the life of African Americans in ferguson, baltimore, north charleston, other places around the United States. Do you think the awareness that has risen through these garage traj dees has changed anything, white people watching, google jane elliot, she has an experiment, the blue and brownide experiment. I encourage people to watch that, it will actually grow you. You no, back to stuff that will make you laugh. If white people are now just discovering that its bad for black or working class people in america, theyre a lot more blind than i thought and theyre a lot more choosing to be ignorant than i thought. The same problems were discussing today we discussed in 1990, 1980, 1970, and 1960. And until we call a spade a spade and this problem is coming from conditions were creating or allowing to happen as a white group of people who hold a certain amount of power do you think theres a systemic attempt in the United States to isolate poor and minorities, to put them in communities that can be controlled . Its not an attempt at all. Its successful. If you look at daly and the highways in, which he built the highways to seg gailt people. Theres no roundabout way to do it. Absolutely. Stephen again, speaking we what can we do to bridge the gap between the communities of color . Should you you own barber shops. Should white people start getting their hair cut at black barber shops . I hope so. Stephen because there are conversations going on at those barber shops that were not part of. And white people pay 50 for hair cuts, so, absolutely. I would like that. I would like that. cheers and applause i speak at colleges often, and when i speak at black colleges, and i speak at white colleges, a slightly different message. The message they preach to white kids that are in tallahassee, atlanta, georgia tech, places like new york, is get outside the college environment, find a child who is marginal or doing exceptional in school who is a minority, doesnt look like you, not of the same religion, not of the same background, help that child matriculate into college. Help them by being a big dont give them gifts and make yourself feel good, hey i bought teachers. What youre going to get out of that experience is another human being taking full advantage of an educational system that can help them in their community. But it grows you as a human being to have empathy for someone who didnt look like you and is culturally not from your background. Stephen speaking of cument rally, speaking of culturally weve only got a minute here. Speaking of people not culturally from your background, youre feeling the bern. You like bernie sanders. I do. Stephen okay, as quickly as you can, tell me why you believe bernie is the man. Dr. King in hills last two years of life talked about a poor peoples campaign, organizing unions on behalf of poor workers, organizing against the war machine that was perpetuating violence in vietnam. Berpy sanders is the only politician who has consistently for 50 years taken the social justice platform into politics. And right now we have an is directly out of the philosophy of kingian nonviolence. We can directly elect someone who cares about poor people, cares about women, gay, black rights. Cares about lives that dont look like his help and this opportunity in history is not going to come in another 20 years, not going to come in another two years. cheers and applause if we do not take this opportunity right now, were going to be sitting around a campfire mad because theyve niewkd the world to hell, im afraid, you know. Stephen i hope that doesnt happen and i hope you come back. Killer mike. Stay right there. Killer mike, everybody. Run the jewels. Among other things. Barber shops. Well be right back. Dad, you can just drop me off right here. Oh no, ill take you up to the front of the school. Thats where your friends are. Seriously, its, its really fine. You dont want to be seen with your dad . No, its. No. This about a boy . Dad stop, please. O, theres tracy. [ horn honks ] what bye dad it brakes when you dont. Forward collision warning and autonomous emergency braking. Available on the newly redesigned passat. From volkswagen. Cottonelle cleanripple texture but will it get people clean enough to go commando . Did you just wipe your bum . Well, i sure did. About the texture . Its very. Functionally this is the equivalent it just gets a hold of everything. Nothings left behind. To go commando . laughs are you serious . Totally. Okay okay how do you feel . Oh my goodness, its amazing. Only cottonelle has cleanripple texture so youre clean enough to go commando. Phil oh no. under his breath hey man hey peter. unenthusiastic oh. Ha ha ha joanne . Is that you . Its me. You dont look a day over 70. Am i right . R jingle jingle. If youre peter pan, you stay young forever. Its what you do. If you want to save fifteen percent or more on car insurance, you switch to geico. You make me feel so young. Its what you do. You make me feel ,,,, cheers and applause stephen welcome back, everybody. My next guest is a harvard medical professor, a biologist, a geneticist, a chemist, and an engineer whose work with d. N. A. Is transforming our biology and our future. Please welcome george church. cheers and applause stephen george. Please, have a seat. That was how was your ride on the science mobile . Oh, it was very energy efficient. laughter applause stephen its thats a brand new stage, science boy. laughter thats coming out of your check. George, thanks for nice to see you again. Yup. Stephen now, for the people who dont know, youre a professor at Harvard Medical School where you run the church lab. Youve already transformed biology when you helped map the human genome. Youre not editing d. N. A. To fight disease and resurrect and i think species. How do you edit d. N. A. . So there are a wide variety upon the one thats attracting the most attention now is crisper. Its kind of a buzz word crisper, that sounds like an app. Yeah, its a big app. laughter tiny molecular machine, and with 20 a. C. G. S and t. S you can program it to go wherever you want and cut d. N. A. Stephen in someones body . Yes, in gene therapy, in human cells. Stephen what you can do with it . How are humans being modified right now . Can you give me wolverine claws . What yeah. Stephen whats being done right now with this . I think youre better off without them. laughter so right now, its being applied to things as diverse as eliminating malaria, by working mosquitoes. Stephen malariaresistant mosquitoes . Yeah. Stephen so we cure the mosquitoes so we cant catch it from them. Thats cool. Thats like curing werewolves so yeah. There you go. Stephen yeah, yeah. And h. I. V. And hepatitis. So the crisper actually is designed or came from bacteria, where it would kill viruses. Where does it live . So it normally lives in bacteria, and its been transplanted we and others turned into technology where it can now work in plant and animals and human cells. Stephen so youre taking, like, this d. N. A. From a little bacteria, and youre injecting it into plant and animals. Doctor . Hopefully, there will be lots of safety and efficacy testing. Stephen arent you playing god or are you just laughter applause what is yeah. Stephen you must hear the playing god thing a lot, right . Yeah, i think the were not in that league at all. I mean, creating the universe in a couple of seconds, its more like were playing engineer or working at being engineers, procedures. Stephen can we grow organs now . Could you use gene therapy to grow me a new organ . Differentiate into very complicated tissue including brain and lungs and so forth. Stephen how long will i live now . Im 51. Is there a chance this gene therapy is going to extend my life or is it only for people being born now . Yeah, i think well, we have demonstrations in animals at aging reversal. You can see a wide variety of what where you can get blood vessels, skeletal, cardiac muscle and so forth give them to me. I have to cut a check, i bet. Right . Its who you know. Thats how you live forever, its you who know. Yup, now i know why im on the show. Stephen can you bring back the wolly mammoth . I would love to see one. Id love a wooly steak. Can we get one . laughter . We can read the wooly mammoth genome, which is pretty amazing. And we can now write it. We can edit the genomes with crisper and weve done this. Weve made 15 edits of bringing back and i think d. N. A. Stephen please grow one and bring it back on the show. That would be fun. Thats serious ratings. Thats serious ratings. Weapon, thank you so much. Also, the wolverine clause, im up for those, too. Thank you for being here. George church, everyone. Were all going to live forever. Well be right back. cheers and applause come seek the royal caribbean. Olive garden s allnew flavorfilled pastas, with raviolis so nice we filled them twice. Bursting with indulgent flavors like chicken marsala ravioli, or smoked mozzarella manicotti. Plus unlimited salad and breadsticks. Starting at 12. 99. For a limited time. Take one of those pillows and take a big smell. They smell really fresh what if we told you we washed these sheets 7 days ago. Really . No way downy . Downy fabric conditioner give us a week, and well change your bed forever. Want more freshness . Add new downy fresh protect. Why is Philips Sonicare the most loved electric toothbrush brand by americans and their dentists . 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I see it more and more each day what i give, it takes away whether i go or when i stay i see a mountain at my gates i see it more and more each day i see a fire out by the lake ill drive my car without the brakes i see a mountain in my way its looming larger by the day i see a darkness in my fate ill drive my car without the oh, gimme some time show me the foothold from which i can climb yeah, when i feel low you show me a signpost for where i should go i see a mountain at my gates i see it more and more each day and my desire wears a dark dress but each day, i see you less oh, gimme some time show me the foothold from which i can climb yeah, when i feel low where i should go through lanes and stone rows black granite, wind blows fire lake and far flame go now but come again dark clouds gather round will i run or stand my ground oh, when i come to climb show me the mountain so far behind yeah, its farther away its shadow gets smaller day after day gimme my love gimme my choice you keep me coming around gimme my fate gimme my lungs gimme my voice you keep me coming around gimme my lungs gimme my, gimme my gimme my, gimme my gimme my, gimme my gimme my, gimme my gimme my way gimme my fate gimme my lungs gimme my choice you keep me coming