Right now. Announcer from nbc news World Headquarters in new york, this is nbc lester holt. Good evening. Its d bate night. Hillary clinton and Bernie Sanders in their first oneonone debate, just five days hampshire primary. It comes as a brandnew nbc news wall street poll showingglinton with milele of ground to make up. 58 of likely democratic voters in New Hampshire are backing sanders. Clinton with 38 . Thats virtually unchangege from a week ago. Sosotonight, from clinton, a change of tone, and a direct challenge to sanders on who claims the progressive. Lets get the view om both camps starting with nbcs andrea mitchell. Reporter good evening, lester. Not only is it going into the debate, does the new poll show bernrn sanders is hampshire, but he has a slight lead among women. And a giant lead with as Hillary Clinton prepepes for tonights showdown, her top target, reaching young voters and women. Our new nbc news wall street journal maris poll showing clinton losing the youth vote to sanders by a whopping 22 . Among women, she trails by 4 . And young women, 29 . Clinton is noticeably toning down those sharp edges she showed in iowa. I will stand up and fight for you every single day of this Campaign Reporter showing her softer, more reflective side in New Hampshire. A rare glimpse last night. Ive had to be in public dealing with some very difficult issues. And personal issues. Reporter revealing sheelies on a jesuit parables. One of her strongest moments of this campaign. She also touted her progreive credentials. Who gets results, and i will be a progressive president that will get results. Reporter struggling to answer why she took 675,000 in speaking fees from wall street banks. S. Well, i donon know. Thats what they offered. Reporter her ties to wall street, attacked from bernie nders, and sure to come upp tonight. Andrea mitchell, nbc news, durham, New Hampshire. Im casey hunt with the sanders campaign. Rallying the troops s before his oneeone debate with Hillary Clinton. I look around this beautiful room, and i sense that people here want to make a political revoludion, am i right about that . Reporter tonight expect Bernie Sanders to once again go after clinton with the question, whos the most progressive . Do you think Hillary Clinton is a progressive . Somedays, yes. Reporter his campaign taking to twitter. The progressive united in saying, dont listen to bush. Reporter key for sanders tonight, reaching older voters. Our new poll showing the majority of New Hampshire older voters back hillala clinton. Sanders message is already hitting home for young people. Like these students at the univivsity of new hampshshe. Ive got a friend in bernie reporter managinin expectations is another concern for sanders. Hes so far ahead right now, if Hillary Clinton does manage to close that gap, it could still be a problem for him, even if he comes in first. Lester. Casie, thank you. Check todd is comoderating the debate on msnbc. Chuck sanders long considered the frontrunner in the New Hampshire race. Does that take any pressure off secretary clinton in this you know, i dont think it does, only because of the clinton tradition here in New Hampshire. New hampshires been very good to the clinton family. Saved bill clintos candidacy in 1992. Helped extend hillarys race in 2008. I dont think necessarily it buys her time. But look, this debate is coming at a time when the two of them are having a real bate about what should the Democratic Party be. Should it be what its been . Is it the party of obama and clinton . Or does it need to go in a new direction as Bernie Sanders . Clearly an army of supporters wants t t take it. Chuck, thanks very much. Tonights msnbc democratic debate kicks off live from the university of New Hampshire, comoderated by chuck, and Rachel Maddow at 9 00 eastern time. N the republican race, another new poll shows marco rubio leaping over ted cruz in New Hampshire, to takehe number two spot behind frontrunner donald trump. As nbcs Hallie Jackson tells us, rubios adversaries reporter with momentum in new rubios hoping for a photo finish, drawing crowds in every shot take eirs. Being here. Reporter sparked by thiss slip, Rick Santorum endorsing rubio, but seeming to struggle when asked why. Can you name his top accomplishment . My feeling on marco someone who has tremendous potential, tremendous gifts. You loo at the minority in thenited States Senate in a year when got done, its hard to say there are accomplishments. Reporter rubios competitors desperate to gain ground in new sham shire. Is whole life has been around his own ambitions. Hes gifted. He can turn a phrase really well. But what has he done. The fact is, this is a guy whos only done one thing in the united States Senate, that is write an amnesty bill for the the va and fighting human trafficking. We have real achievements, not just in the u. S. Senate but my time as speaker of the housesend as a state legislator. Reporter rubio trying to stay above the establishment fray and so is john kasich, campaigning at concord high school. Are you the president . Yes. Did y y run a negative mpaign . Wouldnt it be great you could run for president just like you run for class president , where you just tell people what youre for, instead of spending your time trashing somebody else. Reporter Donald Trumps trashing everyone else, slammi all politicians in typically trump fashion. I was going to say theyre full off [ bleep ], but i w wt say that. While trump still leads in new hoping for a boost with help from his mom. Barbara bush will be here tonight. , appearing together on the campaign trail. Former drug company ceo who some have called the most hated in ameri anger on capitol hill today. Martin shkreli refused to testify before congress and later insulted them. Anne thompson has the tails. Reporter appearing to smirk are you listening . Reporter and often inattentive. Yeah. Reporter former pharmaceutical ceo Martin Shkreli lived up to his badboy reputation appearing before congress. I intend to use the advice of my counsel, not yours. Reporter posing for pictures instead of listening. Its not funny, mr. Shkreli, people are dying, and theyre getting sicker and sicker. Reporter he declined to answer why he raised their lifesaving drugs 5,000 . Do you think youou did anythinin wrong . O o advice of counsel, i invoke my fifth amendment privilege. Reporter the 32yearold usually im from the streets. Reporter but today he let his attorney speak for him. What you saw was Nervous Energy by an individual who very much would like to explain what happenen. Reporter r eaving the other drug Company Executives to face furious questioners. I find it repulsive what youve done. Reporter valiant ynder fire for jacking up prices onwo heart medicicis and other wellestablished drugs. Where weve made mistakes, were listening, and were changing. Reporter determined to hav the last word, shkreli took to twitter calling the anne thompson, nbc news, new york. Fears over the zika virus have led florida to expand its state of emergency to cover five unties. Governor rick scott said that the 12 cases didiovered in florida are from infections outside the u. S. But teams are out in force in south florida mosquitoeshat carry zika. Scott is also asked the c c for 1,000 more rapid zika test kids. We turn now to the long and bloody war in syria, and new drone video that shows the utter devastation of the c cy where 1 Million People lived before the war. Today the u. S. Pledged an additional 600 million to aid reregees. While thoseseho canan get out face growing desperation. It includes those in a town outside damascus where the red cross said is getting close getting aid to. Disturbing details of what people are facing there. Heres our chief Foreign Correspondent chard engel. Reporter theyre slowly being exterminated exterminated. Thats a syrian helicopter dropping explosives, killing danny, the activist who took this video, told us bombs rain down up to 30 times a day. He sent us another video of muhammad, a malnourished 11yearold whose father says is too weak to walk. He said these videos are the only thing he can do for his people. We see them and we cant do anything for them. They are dying in front of our eyes. Reporter the Government Cut off the city as punishment for its resistance. Syrian Opposition Forces are doing the same thing to government strongholds, in the middle. So many suffering people. This situation, this siege continues like this for a week or less, hundreds of course. Includinggme anymore. Reporter theres no power either, so danny spoke to us by the light of a small solarpowered lamp. When was the last time i had some olives. People are dying in the cities all around syria. And nobody remembers them. Nobody cares about them. Nobody tries anything to stop is, this disaster. Reporter which is why danny risked everything to take these images, so the world hears 5yearold crying out to her mother. Who has no medicici, food, or milk to give. Richard engel, nbc news. Horrible reality of huge methane gas leak that hasffected thousands of families in a los angeles neighborhood. Tonight we have exusive access. A scientist went up in the air to check on the air. Steve p pterson was with him. Reporter it is the countrys invisible disaster, a plume of methane gas streaming seen here in infa red pouring out of a natural gasell above the community of porter ranch. The amount of methane spewing out is impossible to measure from the ground. This is one of our biggest leaks. Were here to measure it. Reporter to gather the data, you have to fly into it. Scientist dr. Steven connelly in a ecially outfitted plane to get data. The data estimates more than 200 Million Pounds of methane have poured out. Thats as much Greenhouse Gas emitted by nearly half a million cars each year. Its 20 or 30 times as large as the next biggest one that weve seen. Reporter that realization in the air led to a hundred days of heart ache on the ground. David and his daughter are among 5,000 families living in teuporary housing. ,walking in the five or ten minunus, to walk my dog, i couldnt breathe. Reporter he said the rate of the methane has significantly slowed. They say the reservoir will be drained, well capped by the end of the month. Were working really hard and safely to stop this situation and bring tm home. Little comfort for families waiting to go home, as the invisible threat hangs in the air. Steve patterson, nbc news, over porter ranch, california. Still ahead here tonight, protecting the shub. We flies with the eyes in the sky and go inside the fbi nerve center tasked with securing the biggest sporting event of the year. The evidence of the plane with the it takes a lot of work. To run this business. But i really love it. Im on the move all day ng. Bnd sometimes, i just dont eat the way i should. So i drink boost to get the nutrition that im missing. Boost complete nutritional drink has 26 essential vitamins and minerals, including calcium and vitamin d to support strong bones and 10 grams of proteinto help maintaininuscle. All with a great taste. I dont plan on slowing down any time soon. Our parents worked hard so that we could enjoy lifes simple pleasures. Now its our turn. Im doing the same for m m family. Retirement and Life Insurance solutions from pacific life can help you protect what you love and grow your future with confidence. Pacific life. Helping generations of families achieve it is the biggest sports event of the yearl and now the super bowl is also one of the countrys largest security operations. The San Francisco bay area gets set to host the game, dozens of Law Enforcement agencies are gearing up. National correspondent migu almaguer shows us how theyre curing the city by land, sea and air. Reporter with more than 1 Million People pouring into San Francisco for the super bowl, the only thing bigger than the game may be security. The fbi leading 60 agencies on the ground, in the air and at sea. This is by far the most significant securiri presence in the bay area for sure. Reporter with bombsniffing dogs, xray machines, and Sharp Shooters positioned on rooftops, surveillalae on the ground is also key. The bay area is wired, cameras, hightech centers and video feeds are recording hundreds of images every second o streets just like this one. Much of that surveillance is being beamed right back into one room. This is the fbis Central Command center, where they quararrback the Law Enforcement bling. The bad guys have to get lucky once. We have to get lucky every day. Reporter this year air teams face unique challenges. Levi stadium is 45 miles from San Francisco. Theyre watching every bridge and major roadway for anything unusual. O game day, air space will be stricted, but not for blackhawks like these flying in tandem, taking part in sincs with folks inn the bay. Reporter patrolling up to 200 nautical miles out to sea. Our job is to use our training and experience and notice when things may not be 100 what they should be. Reporter the threat could come from anywhere. Its not just the super bowl that makes the bay area a security concern. Its a ao a status as a symbolic american city. A city where all eyes will soon be on the super bowl. But not everyone will be watching the game. Miguel almaguerer nbc news, San Francisco. Were back in a moment with millions more air bags being reca [burke] at farmers, weve seen almost everything, so we know how to cover almost anything. Even turkey jerks. [turkey] gobble. [butcher] im sorry burke covered march fourth,2014. So we know how to cover almost anything. We are fafaers. Bumpadum, mbumbumbum hey sweetie, its time. Eye of the tiger tv anncr od afternoon everyone. Tv anncr its the perfect day for a game of football. Tv anncr this team is having a fantastic season. Morning rituals are special. Whwh you share what you love. With who you love. Kelloggs frosted flakes. Theyre grrreat now. You can win a Microsoft Surface 3. En you buy any speciallymarked kelloggs product. A heart attack doesnt care if you run everyday, or if youre young or old. No matter who you are a heart attack can happen without warning. If youve had a heart attack, a bayer aspirin regimen be sure to talk to your doctor before you degin an aspirin regimen. Bayer aspirin. Im billy, and i quit smoking with chantix. I had a lot of doubts going in. I was a smoker. Hands down, it was, thats who i was. After one week of chantix, i knew i could quit. Along with support, Chantix Varenicline is proven to help people quit smoking. Chantix definitely helped reduce my urge to smoke. Some people had changes in behavior, thinking or mood, hostility, agitation, depressed mood and suicidal thoughts or actions while taking or after stopping chantix. Some had seizures while taking chantix. If you have any of these, stop chantix and call your doctor right away. Tell your doctor about anyny history of Mental Health problems, which could get worse or of seizures. Dont take chantix if youve had a serious allergic or skin reaction to it. If you have these, stop chantix and call your doctor right away as some can be fethreatening. Tell your doctor if you have heart or blood vessel problems, or develop new or worse symptoms. Get medical help right away if you have symptoms of a heart attack or stroke. Decrease alcohol use while taking chantix. Use caututn when driving or operating machinery. Most common sideaffect is nausea. Ask your doctor if chantix is right for you. Hillary clinton is not the only one dealing with email questions. State Department Officials have determined that classified information was sent to the personal email account of former secretary of state colin powell, and senior aides to form secretary condoleezza rice. Powell told nbc news went to his personal account. A spokesman for rice said the emails were about diplomatic conversations and contained no intelligence information. Multiple sources tell nbc news that the force that ripped a hole in a passenger plane over somalia was likely from a bomb made of military grade explosives. Investigators did find explosive residue in the aftermath, but if it was a bomb, no terrorist group has claimed responsibility yet. More air bag recalls, millions more. Honda says another 2. 25 millionaire bags made by takata will have to be replaced in certain honda and acura models. Another air bag manufacturer announced its own recall involving potential air bag problems in up to 5 million hohda, fiat, chrysler and mercedes models. A sad note to report in the music world. Maurice white died. He started the band in the late 1960s, and sell more than 90 million albums worldwide. The group won six Grammy Awards and inducted in the rock 3n roll hall of fame in 2000. White battled parkinsons disease for more than two decades. He was 74 years old. Up next here tonight, you dont have to wait for the super bowl to see every day you read headlines about businesses being hahaed and intellectual property being stolen. That is cybercrime and it affects each and every one of us. Microsoft created the digital crimes unit to fight cybercrime. We use t t microsoft cloud to visualize information so