how you can take control of your crohn's with skyrizi. ♪ ♪ control is everything to me. ♪ ♪ learn how abbvie could help you save. if advanced lung cancer has you searching for possibilities, discover a different first treatment. immunotherapies work with your immune system to attack cancer. but opdivo plus yervoy is the first combination of 2 immunotherapies for adults newly diagnosed with non-small cell lung cancer that has spread, tests positive for pd-l1, and does not have an abnormal egfr or alk gene. opdivo plus yervoy is not chemotherapy, it works differently. it helps your immune system fight cancer in 2 different ways. opdivo and yervoy can cause your immune system to harm healthy parts of your body during and after treatment. these problems can be severe and lead to death.