The Hidden Chamber now being used in the war on cancer. Nightly news begins right now. Good evening. There are calls for calm as gather in baltimore, hours after a jury failed to reach a verdict in the trial of a Police Officer in a case that triggered riots throughout the city in april. It was the first of six Police Officers charged in connection with the death of freddie gray who died while in police custody. Late today the judge declared a mistrial in the case of officer William Porter who was accused of manslaughter and now the decision whether to retry him. Nbcs ron mott with late details. As word of a mistrial spread, cries of protest and scuffles. A jury of seven blacks and five whites failing to reach a verdict in the case of William Porter, charged with manslaughter in the death of freddie gray. Tonight his family and supporters remain hopeful justice will be served. This is just a temporary bump on the road to justice. We are calm. You should be calm too. Reporter the state argued porter showed indifferent to gray while not securing him in a seat belt following his arrest last april in a van and not getting him medical help. The jury deadlocked, on all four counts porter faced, including seconddegree assault and Reckless Endangerment and misconduct in office. Gray suffered a broken neck and died a week later. Touching off more than a week of fiery riots, the worst violence in the city in decades. This admitted gang member sought to squelch today hours before the mistrial announcement. You are mad and angry and want to tear stuff up. I understand. But that is not the right way to go. Is it worth retrying him . I would like to know the divide in the jury. Reporter legal analysts contend the mistrial could make upcoming cases against five other Police Officers including the van driver charged with seconddegree murder even more challenging for prosecutors. This was one of the easier cases to defend because he was not one of the principals that placed freddie gray in the situation he was in. Reporter and tonight city officials also called for calm. All of us, if we believe in justice, must have respect for the outcome of the judicial process. Reporter the family of freddie gray had already reached a 6. 4 million settlement with the city, a city bracing for what could be a long night of demonstrations. The second trial set to start next month and the defendant is the officer who drove that van. Ron mott, thanks. Big news about the economy tonight and it affects everything from your mortgage to your 401 k . For the first time in nearly a decade, the Federal Reserve raised Interest Rate a quarter point. It is a major sign the economy is improving. On wall street stocks finished up across the board. But after years of the cost to borrow money being virtually nothing it is getting more expensive. Our Business CorrespondentOlivia Sterns explains. Reporter like so many families, the hepners new this day would come and when they found their dream home, they acted fast. Our feeling is that if Interest Rates go up and you are paying more per month on your mortgage that is less of a house you could buy. Reporter and today, a week after they moved in, the Federal Reserve voted unanimously to raise the Interest Rate affective immediately. It reflects the committees confidence that the economy will continue to strengthen. Reporter the increase will affect rates on everything from credit cards to 401 k s, mortgages and car loans. The hike is just a quarter of one percent, but the fed is expected to raise rates. The impact is almostin consequential, but it mounts over time. So if we get down the road over 12 months and they hike the Interest Rates a few more times, that is when you notice. For a family looking to take out a 300,000 mortgage, the quarter percent rate hike could mean paying additional 530 per year. If they raise it twice more, that payment would jump by nearly 1,600 a year. But a rate hike isnt all bad news for your wallet. It helps encourage saving, may lead to more income for retirees and a stronger dollar is good for americans traveling abroad. Despite the hike, rates are still near alltime lows. And Americans Still looking for their dream home still have time to buy. And lester, the focus is on how fast the rates go up the next 12 to 18 months, the fed said the rates will go up gradually and only if the economy continues to improve. The last thing they want to do is raise them too fast and knock the recovery off course. Olivia, thank you. And last nights republican president ial debate was one of the fiercest so far. Senator marco rubio had one of the most talked about performances of the debate. And today Hallie Jackson traveled exclusively with him, and donald trump came out swinging. Donald trump sticking the landing on a victory lap, like he is the nominee, a day after promising if he is not, he wont run as an independent. Im totally committed to the republican party. I feel honored to be the frontrunner. Reporter the donald trump battle everyone expected with ted cruz never materialized. But one with jeb bush did. You will never be president of the United States by insulting your way to the presidency. Last night i have jeb come at me. Low energy. And in another corner, cruz versus rubio hammering over National Security and immigration. The ted cruz rule out ever legalizing people in this country senator . I will i have never supported legalization and i do not intend to support it. Cruz counter punch aimed at the pathway to citizenship, part of the Immigration Reform he tried to pass in 2013. Now a liability. Do you regret having been a part of that process . No. I went to washington to solve problems. So why raise it now . You cant do it on one piece of legislation. I do not believe it is good for america to have millions of people permanently living here that could never become americans. Our interview part of a fastmoving day on the campaign trail. In New Hampshire and in iowa. Do you always have the Des Moines Register on the plane. No. Only when we are here. Were happy about the headline today. Sfwlfrnlts the lead story, in a state where he campaigned less than ted cruz. Im motivated by speaking to people because that is where i am and where i come from. I feel very confident and optimistic about it. Reporter and while rubio still trailed his republican rival in iowa, both sit behind the frontrunner nationally. In this republican race, there is donald trump and then everyone else. Just like trump. Just like trump. It is a little smaller. I know. Reporter nationally nobodys poll numbers in the race are just like donald trump. But across the early states cruz and rubio have become part of the top tier. Those three candidates have the momentum before last nights debate and they still have it heading into the holiday break. Lester. Hallie jackson, thanks. In southern california, back to normal after hundreds of los angeles schools reopened after the hoax in the second Largest School district. Crisis counselors were on hand for kids who wanted to talk about what happened. The fbi is still trying to determine who was behind the threats. There are new revelations in the investigation of the terrorist attack in San Bernardino. What the fbi is now saying about reports the female killer posted jihadist messages on social media that werent caught during a background check to earn her visa to the u. S. Our justice correspondent Pete Williams on the trail of terror. It is an urgent question. Why did the government give malik a visa to enter the u. S. If she was posting projihadist messages before she got here. Simple, said the fbi director, she never did post messages back then. She sent only emails and direct private communications to her fiance in the u. S. , farook. So far in the investigation we have found no evidence of posting on social media by either of them at that period of time and thereafter reflecting their commitment to jihad or martyrdom. Reporter around the time of the shooting, malik did post a pledge of support for isis on a facebook timeline. Comey said the fbi has found no indication that the couple was in direct contact with any Foreign Terror Organization before the shooting or part of a cell. Still unanswered, he said, what else were they planning. Also today, the secretary of Homeland Security said he will begin issuing periodic bulletins to describe the changing nature of the terrorist threat nationwide. Without raising the overall threat level as the old system did or waiting for specific threats. We want to put in one place for the public to see what we are seeing concerning the homeland and what we are doing about it and what the public can do about it. Reporter the first such bulletin on the dhs website today describing the general threat of selfradicalized extremists who could strike with little or no notice. Future bulletins may advise more screening lines at Public Events like the super bowl or when security is ramped up. And tonight the white house said the president will meet with shooting victims and family members in San Bernardino on friday. He will then head on to hawaii with his family for the holidays. Pete, thanks. A new study out today could change the way doctors treat an all too Common Health emergency. For decades the goto treatment for appendicitis is surgery. But now as rehema ellis explains, doctors are exploring a new option for children that may eliminate the trip to the operating room. Today this 12yearold remembers the painful appendicitis that nearly ruined his familys trip to disneyworld. It was kind of like somebody was stabbing me over and over again every time i would move. She had never been sick like this before so i was very afraid for her safety. Reporter but instead of surgery, she was treated with antibiotics. Being the first study on using them for early and mild cases of appendicitis in children. She was able to go home a day or two later. Reporter the small study found with antibiotics alone, 95 of the children improved within 24 hours and were discharged without undergoing surgery. A recent study in europe showed similar success for adults resulting in less Recovery Time and lower health costs. The classic symptoms of appendicitis include pain around the naval, moving to the right side. Also nausea and fever. The new study found one in four young patient cases were mild enough to avoid surgery. In order to meet that criteria, you have to have pain for less than two days an the inflammation has to be contained within the appendix. So there is no sign it is about to rupture or has ruptured. Reporter and for most it didnt flareup again. They didnt say you must have surgery or you must have antibiotics. We were able to choose and that was a wonderful thing for us. Reporter a choice that worked for the gibsons who made it to disneyworld and she has been symptomfree for two years. Rehema ellis, nbc news, new york. Still ahead, tonight exclusive access inside of the top secret Los Alamos Nuclear lab where the Technology Behind the most destructive weapons known to man is being used instead to save lives from cancer. D i woman its been a journey to get where i am. And i didnt get here alone. There were people who listened along the way. People who gave me options. Kept me on track. And through it all, my retirement never got left behind. 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It will be known as one of the birthplaces of the atomic bomb and also being used to develop a very different kind of weapon. One that puts los alamos on the cuttingedge in the battle against cancer. Nbcs Janet Shamlian has more on our special series of reports, target cancer changing the cure. Reporter tucked away in the mountains of new mexico. Los alamos, a top weapons Nuclear Weapons lab. Today at the forefront of groundbreaking research that could change the fight against cancer. We obtained access to the highly secure compound. Where eva burnbalm showed us how they are manufacturing a radioactive treatment that targeted tumors but doesnt kill the healthy tissue around that. This glass window is several different panes of leaded glass about three feet thick to offer us protection from the radioactivity. The material so toxic, Scientists Use robotic arms to work with them. So that piece that has to be lifted up and placed on top of the other piece, just like that. Very good. Reporter here is how it works. A metallic disk is blasted with a proton beam, making a cloud of radioactive particles partnered with a protein to make actinium 225. Think of it as a laser guided missile injected into the body and traveling directly to cancer cells. In terms of breakthroughs in Cancer Treatment in the past couple of decades, how important is this . I think this is tremendous. If we could get the pieces to work together, this should be a very affective way to treat cancer in the future. This doctor tested the therapy on leukemia patients in a clinical trial. Some went into remission. This is a more focused radiation and more precise and allowed sufficient killing of the targeted cell alone. Reporter doctors hope this massive equipment at los alamos will boost production and help patients with many cancers. I think well see faster progress and see this going global. Reporter Nuclear Technology once used for destruction now focused on saving lives. Janet shamlian, nbc news, los alamos, new mexico. Tomorrow in our series, the quick freeze therapy being used to prevent the Fastest Growing forms of cancer in america. When we come back, are medical choppers used too often . Serious safety questions tonight after yet another one went down in phoenix. Often. Serious safety you owned your car for four years, you named it brad. You loved brad. And then you totaled him. You two had been through everything together. Two boyfriends, three jobs. Youre like nothing can replace brad. Then Liberty Mutual calls, and you break into your happy dance. If you sign up for better car replacement™, well pay for a car thats a model year newer with 15,000 fewer miles than your old one. See Car Insurance in a whole new light. Liberty mutual insurance. Where our next arrival is. Red carpet whoa toenail fungus . Fight it with jublia. Jublia is a prescription medicine used to treat toenail fungus. Use jublia as instructed by your doctor. 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