Data: CDC and New York Times; Chart: Will Chase/Axios The counties with the most vaccine-hesitant residents generally also voted for Donald Trump in 2020 by large margins, whereas the counties with the lowest levels of hesitancy generally also had fewer Trump voters. Why it matters: Your politics don't have anything to do with whether you're vulnerable to the coronavirus if you remain unvaccinated. In fact, many counties with high levels of vaccine hesitancy — particularly in the South — are also considered by the Centers for Disease Control and Prevention to be highly socially vulnerable based on factors like poverty, lack of access to transportation and crowded housing.