email article When it comes to identifying primary hyperparathyroidism (pHPT), choline positron emission tomography and computed tomography (PET-CT) may be the way to go. In a meta-analysis of 119 comparative studies, choline PET-CT had the highest sensitivity for localization of primary hyperparathyroidism, Seong-Jang Kim, MD, PhD, of Pusan National University Yangsan Hospital in Korea, and colleagues reported in When compared with other imagining techniques including technetium (Tc) 99m sestamibi (MIBI) single-photon emission computed tomography (SPECT), choline PET-CT had significantly higher sensitively in both a patient-based analysis (OR 5.22, 95% credible interval [CrI] 2.36-11.80) and a lesion-based analysis (OR 17.70, 95% CrI 5.79-60.10). The researchers also classified all imaging types into eight representative imaging categories. Among these, choline PET-CT had the highest surface under the cumulative ranking curve (SUCRA) value in both patient-based and lesion-based analyses.