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GSRGT 2020: Management of Chemotherapy-Resistant Germ Cell Tumors in 2020


GSRGT 2020: Management of Chemotherapy-Resistant Germ Cell Tumors in 2020
(Urotoday.com) To kick-off a series of lectures discussing testicular cancer at the inaugural meeting of the Global Society of Rare Genitourinary Tumors (GSRGT) 2020 virtual summit, Dr. Andrea Necchi provided the keynote lecture discussing the management of chemotherapy-resistant germ cell tumors. Dr. Necchi started by highlighting the global incidence and mortality of germ-cell tumors:
As follows is an overview of first- and subsequent salvage treatment options:
10-20% of patients will progress/relapse after first-line therapy
A proportion varying from 25% to 60-70% of patients with will be cured by second-line treatments
There are very few randomized trials to guide treatment decisions ....

United States , New Zealand , Zachary Klaassen , Andrea Necchi , Indiana University , Augusta University Medical College Of Georgia , Global Society Of Rare Genitourinary Tumors , Scientific Institute , Cancer Trials Group , Salute San Raffaele University , Georgia Cancer Center , Global Society , Rare Genitourinary Tumors , New Zealand Urogenital , Associate Professor , Vita Salute San Raffaele University , Genitourinary Medical Oncology , Raffaele Hospital , Assistant Professor , Medical College , Rare Genitourinary Tumors Virtual Summit , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஜீலாந்து , சக்கரி க்லாஸ்சேங் , ஆண்ட்ரியா னேக்சி , இந்தியானா பல்கலைக்கழகம் ,

GSRGT 2020: Management of Chemotherapy Resistant Germ Cell Tumors in 2020


GSRGT 2020: Management of Chemotherapy Resistant Germ Cell Tumors in 2020 - Keynote Commentary
(Urotoday.com) To provide a context to the keynote lecture by Dr. Andrea Necchi discussing the management of chemotherapy-resistant germ cell tumors at the inaugural Global Society of Rare Genitourinary Tumors virtual summit, Dr. Lucia Nappi provided a commentary discussion of this topic. By way of background, Dr. Nappi notes that 20-30% of patients will relapse after first-line therapy, and the prognosis after second-line therapy is less favorable, with only 15-30% of patients maintaining a continued disease-free rate. Most studies in this disease space are non-randomized, small, and include a heterogeneous population. Very few randomized studies have shown a higher benefit of sequential salvage high-dose chemotherapy than a single consolidating high-dose chemotherapy cycle after three standard doses. Furthermore, there is a lack of clinical/biological predictive markers for appro ....

United States , United Kingdom , British Columbia , Zachary Klaassen , Andrea Necchi , Lucia Nappi , Indiana University , Urologic Sciences Dpt , Indian University , Cancer Collaborative Group , Augusta University Medical College Of Georgia , Senior Research Scientist Vancouver Prostate Centre , Global Society Of Rare Genitourinary Tumors , University Of British Columbia , Georgia Cancer Center , Memorial Sloan Kettering Cancer Center , Global Society , Rare Genitourinary Tumors , Germ Cell , Assistant Professor , Medical Oncologist , Senior Research Scientist Vancouver Prostate , Medical College , Rare Genitourinary Tumors Virtual Summit , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் ,

GSRGT 2020: Penile Cancer: Conservative N-strategies - Minimally Invasive Staging of the Groin


GSRGT 2020: Penile Cancer: Conservative N-strategies - Minimally Invasive Staging of the Groin
(Urotoday.com) The penile cancer session at the inaugural virtual summit of the Global Society of Rare Genitourinary Tumors (GSRGT) included a presentation of conservative strategies for lymph node management, including minimally invasive staging of the groin, by Dr. Oscar Brouwer from The Netherlands Cancer Institute. Dr. Brouwer notes that penile cancer survival is highly dependent on lymph node status and that appropriate management of the regional lymph nodes is crucial for patient survival. Older studies suggest that early resection of occult metastasis versus resection after the disease is palpable during surveillance significantly improves cancer-specific survival (84% vs 35% at 3 years). As such, detecting lymphatic spread as early as possible is crucial. Dr. Brouwer notes that if there are palpable abnormalities of the groin, there is no place for a trial of antibiotics an ....

United States , Noord Holland , Zachary Klaassen , Oscar Brouwer , Global Society Of Rare Genitourinary Tumors , European Association Of Urology , Georgia Cancer Center , Augusta University Medical College Of Georgia , Netherlands Cancer Institute , National Comprehensive Cancer Network , Global Society , Rare Genitourinary Tumors , Netherlands Cancer , European Urology , European Association , Leeuwenhoek Hospital , Assistant Professor , Medical College , Rare Genitourinary Tumors Virtual Summit , ஒன்றுபட்டது மாநிலங்களில் , நூற்த் ஹாலண்ட் , சக்கரி க்லாஸ்சேங் , ஆஸ்கார் பிரௌவெர் , ஐரோப்பிய சங்கம் ஆஃப் சிறுநீரகம் , ஜார்ஜியா புற்றுநோய் மையம் , அகஸ்டா பல்கலைக்கழகம் மருத்துவ கல்லூரி ஆஃப் ஜார்ஜியா ,