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The FDA has authorized Pfizer's COVID-19 vaccine. Now what? | Coronavirus


Millions of Americans will soon be lining up for COVID-19 shots. 
On December 11, the Food and Drug Administration granted emergency use authorization for the Pfizer-BioNTech vaccine for those age 16 and older. The decision comes as numbers of COVID-19 cases, hospitalizations and deaths have been rising at alarming rates. The United States recorded a record-high 3,411 COVID-19 deaths on December 9.
The United States is the latest country to authorize the vaccine, after the United Kingdom, Canada, Bahrain and Saudi Arabia (
SN: 12/2/20). 
Here’s what happens next in the United States.
The vaccine starts to be shipped, but won’t have a widespread impact for several months. ....

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Gene therapy for mitochondrial disease shows promise in animals


Gene therapy for mitochondrial disease shows promise in animals
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Results from a long-term study of a gene therapy technique to prevent inherited mitochondrial disease show promise, researchers say.
Studies of the technique at Oregon Health & Science University in Portland show no adverse health effects in rhesus macaque monkeys and their offspring. The researchers said the technique could break the cycle of disease passed from mother to baby through mutations in mitochondrial DNA, or mtDNA.
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Though results of animal studies sometimes differ in humans, the findings bolster the scientific basis for mitochondrial replacement therapy, or MRT, in human clinical trials, the study authors said. ....

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