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Lauren Frank , Ruben Petreaca , Renee Bouley , Ryan Yoder , National Institutes Of Health Cancer Institute , Crawford County , Ohio State Marion , National Institutes , National Cancer Institute , Molecular Genetics , Associate Professor , Assistant Professor , Engineering Building , Pelotonia Undergraduate Fellowship , County Now , லாரன் வெளிப்படையான , ரெனீ போலே , ரியான் யோடர் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் புற்றுநோய் நிறுவனம் , க்ராஃபோர்டு கவுண்டி , ஓஹியோ நிலை மரியன் , தேசிய நிறுவனங்கள் , தேசிய புற்றுநோய் நிறுவனம் , மூலக்கூறு ஜெநெடிக்ஸ் , இணை ப்ரொஃபெஸர் , உதவியாளர் ப்ரொஃபெஸர் ,

Most cancer cells grown in a dish have little in common with cancer cells in people

Most cancer cells grown in a dish have little in common with cancer cells in people
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United States , San Francisco , Rachel Gleyzer , Patrick Cahan , Kathleen Dinapoli , Bradley Isaacs , Franklin Huang , Stephanie Cai , Johns Hopkins , Wen Hsin Tai , Pavithra Kumar , Johns Hopkins University , University Of California , Department Of Defense , National Institutes Of Health Cancer Institute , Johns Hopkins University School Of Medicine , International Human Genome Sequencing Consortium , University Of Santa Catarina , Prostate Cancer Foundation Young Investigator Award , Johns Hopkins Medicine , Johns Hopkins University School , Genome Medicine , Cancer Genome Atlas , International Human Genome Sequencing , National Institutes , National Cancer Institute ,

$2.7 Million NIH Grant Supports UNC and Rutgers Cancer Inst.

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William Zamboni, PharmD, PhD
Sha Chang, PhD
New Brunswick, N.J., May 26, 2021 – In the world of cancer therapies, nanoparticles hold great promise for delivering more effective and safer cancer treatment than the standard small molecule drugs that are commonly used today.
William Zamboni, PharmD, PhD, an expert in the pharmacology of nanoparticles at the University of North Carolina Eshelman School of Pharmacy, Sha Chang, PhD, director of medical physics research at UNC, and Rutgers Cancer Institute of New Jersey Director Steven K. Libutti, MD, FACS, whose work involves understanding the tumor microenvironment, are hoping to fight pancreatic cancer using the combination of a novel type of radiation and nanoparticles. The work is supported by a $2,792,913 grant (1R01CA247652-01A1) from the National Institutes of Health s National Cancer Institute. ....

Sha Chang , Edmund Lattime , Stevenk Libutti , Lineberger Comprehensive Cancer Center , Rutgers Cancer Institute Of New Jersey , National Institutes Of Health Cancer Institute , Molecular Therapeutics Program , University Of North Carolina , Rutgers Cancer Institute , Rwjbarnabas Health , Rutgers Cancer , North Carolina , North Carolina Eshelman School , New Jersey Director Steven , National Institutes , National Cancer , Comprehensive Cancer Center , Translational Pharmacology , Analytical Chemistry , Ziqiang Yuan , ஷா சாங் , லிநேபேர்கேற் விரிவான புற்றுநோய் மையம் , ரட்ஜர்ஸ் புற்றுநோய் நிறுவனம் ஆஃப் புதியது ஜெர்சி , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் புற்றுநோய் நிறுவனம் , மூலக்கூறு சிகிச்சை ப்ரோக்ர்யாம் , பல்கலைக்கழகம் ஆஃப் வடக்கு கரோலினா ,

New Insights Into Hormone's Action Could Help in Battle Against Prostate Cancer

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New Insights Into Hormone’s Action Could Help in Battle Against Prostate Cancer
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect genetic activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells – and cancer – interact with androgen. ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Bryce Paschal , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , School Of Medicine Department Biochemistry , National Institutes Of Health Cancer Institute , Cancer Center , University Of Virginia Public , Molecular Genetics , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Virginia Public , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,

New insights into androgen's action could boost battle against prostate cancer

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IMAGE: Bryce M. Paschal, PhD, of the University of Virginia School of Medicine s Department of Biochemistry and Molecular Genetics, has unveiled a new mechanism for how the androgen hormone regulates communication.
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Credit: Angela Paschal
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells - an ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , National Institutes Of Health Cancer Institute , Cancer Center , Virginia School , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Medicine Health , Prostate Cancer , Internal Medicine , Sex Linked Conditions , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,