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Scientists test the effect of natural product isolated from sea sponge on cancer cells

Scientists test the effect of natural product isolated from sea sponge on cancer cells
Scientists from Far Eastern Federal University (FEFU) together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge. One of them fights cancer cells resistant to standard chemotherapy, and at the same time has an interesting dual mechanism of action. A related article appears in
Marine Drugs.
Scientists have tested the biological effect of the marine alkaloid 3,10-dibromofascaplysin on various prostate cancer cells, including those resistant to standard docetaxel-based chemotherapy. The compound was first isolated from the sea sponge Fascaplysinopsis reticulata and subsequently chemically synthesized in FEFU. The substance forces tumor cells to die via a programmed cell death mechanism. This process is called apoptosis and is considered the most favorable mode of action of anticancer drugs. ....

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بحران تیگری؛ آمریکا 'قساوت'‌ در اتیوپی را محکوم کرد

بحران تیگری؛ آمریکا 'قساوت'‌ در اتیوپی را محکوم کرد
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Welcome To IANS Live - SCIENCE - Targeting MAPK4 enzyme may provide therapy for prostate cancer

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New York, Feb 21 (IANS) There is a possibility that targeting the enzyme MAPK4 in human prostate cancer might provide a novel therapeutic strategy for the disease, said researchers.
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Update: 21-February-2021 ....

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تلاش اردوغان برای پوشاندن دردهای اقتصادی ترکیه با جنگ فرهنگی

تلاش اردوغان برای پوشاندن دردهای اقتصادی ترکیه با جنگ فرهنگی
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Welcome To IANS Live - SCIENCE AND TECHNOLOGY - Targeting MAPK4 enzyme may provide therapy for prostate cancer

The study indicates that the enzyme MAPK4 concertedly activates androgen receptor (AR) and AKT, molecules at the core of two cellular signalling pathways known to promote prostate cancer growth and resistance to standard therapy. ....

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