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Janssen Pharmaceutica NV: Janssen Announces Treatment with ERLEADA?(apalutamide) Significantly Improved Overall Survival in Patients with Metastatic Hormone-Sensitive Prostate Cancer


Janssen Pharmaceutica NV: Janssen Announces Treatment with ERLEADA?(apalutamide) Significantly Improved Overall Survival in Patients with Metastatic Hormone-Sensitive Prostate Cancer
FOR EMEA PHARMACEUTICAL TRADE AND MEDICAL MEDIA ONLY NOT FOR DISTRIBUTION IN BENELUX, SWEDEN AND ITALY
Janssen Pharmaceutica NV (Janssen) announced today results from the final analysis of the Phase 3 TITAN study, which demonstrated the continued statistically significant benefit of apalutamide plus androgen deprivation therapy (ADT) in overall survival (OS) in patients with metastatic hormone-sensitive prostate cancer (mHSPC) when compared to placebo plus ADT.
1 Results will be featured in an oral presentation at the American Society of Clinical Oncology s Genitourinary (ASCO GU) Cancers Symposium, taking place virtually February 11-13, 2021 (Abstract #11; Rapid Abstract Session: Prostate Cancer, February 11 9:30 PM-10:15 PM CET). ....

United States , Alexandra Nisipeanu , Noah Reymond , Jennifer Mcintyre , Christopher Delorefice , Axel Merseburger , Asia Pacific , American Society Of Clinical Oncology , Monitoring Committee , Janssen Pharmaceutical Companies , Janssen Pharmaceutical Companies Of Johnson , Exchange Commission , Companies Of Johnson , European Medicines Agency , American Society , Clinical Oncology , Cancers Symposium , Rapid Abstract Session , Prostate Cancer , New England Journal , Professor Axel Merseburger , North America , Latin America , South America , Independent Data Monitoring Committee , Pharmaceutical Companies ,

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model


Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model
A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The
Journal of Nuclear Medicine. The results of the murine study indicate that radionuclide therapy promotes prostate cancer immunogenicity, provoking a cellular response that makes the tumors more receptive to immunotherapy.
Prostate cancer is generally viewed as an immunological cold cancer in which immunotherapies only have moderate success. Increasing prostate cancer immunogenicity with prostate-specific membrane antigen (PSMA) radionuclide therapy, however, might render immunotherapies more successful. In our research we sought to exploit this effect by combining radionuclide therapy with immunotherapy in a mouse model of prostate cancer. ....

United States , University Of California Los Angeles , Emily Henderson , Journal Of Nuclear Medicine , Assistant Professor , Preclinical Theranostics , California Los Angeles , Prostate Cancer , Molecular Imaging , Mouse Model , Nuclear Medicine , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா லாஸ் ஏஞ்சல்ஸ் , எமிலி ஹென்டர்சன் , இதழ் ஆஃப் அணு மருந்து , உதவியாளர் ப்ரொஃபெஸர் , கலிஃபோர்னியா லாஸ் ஏஞ்சல்ஸ் , நோயெதிர்ப்பு சிகிச்சை , ப்ராஸ்டேட் புற்றுநோய் , மூலக்கூறு இமேஜிங் , சுட்டி மாதிரி , அணு மருந்து ,

Boxing: Heavyweight boxing great Leon Spinks who shocked Muhammed Ali dies


Boxing: Heavyweight boxing great Leon Spinks who shocked Muhammed Ali dies
7 Feb, 2021 12:01 AM
Quick Read
Former heavyweight world champion Leon Spinks has passed away. Photo / Getty
NZ Herald
Former heavyweight champion Leon Spinks Jr. has died after battling prostate and other cancers. He was 67.
Spinks died Friday night, according to a release from a public relations firm. His wife, Brenda Glur Spinks, and a few close friends and other family members were by his side when he passed away.
Spinks won gold at the 1976 Montreal Olympics. But he rose in prominence when he beat Muhammed Ali for the heavyweight title in 1978. ....

Spinks Jr , Brenda Glur Spinks , Muhammed Ali , Leon Spinks , Heavy Weight , சுழல்கிறது ஜூனியர் , முஹம்மது அலி , லியோன் சுழல்கிறது , கனமான எடை ,

MRI-targeted biopsy shows value in prostate cancer


February 5, 2021 Multiparametric MRI-targeted biopsy for clinically significant prostate cancer can yield detection rates similar to systematic transrectal ultrasound-guided (TRUS) biopsy, while potentially enabling over one-third of prostate biopsies to be avoided, according to research published online February 4 in
In a multicenter, prospective, and randomized phase III study called PRostate Evaluation for Clinically Important Disease: MRI vs. Standard Evaluation Procedures (PRECISE), a team of researchers from Canada found that providing targeted biopsies after a positive multiparametric MRI scan was noninferior to systematic TRUS biopsies for detecting prostate cancers with an International Society of Urological Pathology grade group (GG) of 2 or higher. ....

Laurence Klotz , Olivier Rouvi , International Society Of Urological Pathology , Sunnybrook Health Sciences Center , Clinically Important Disease , Evaluation Procedures , International Society , Urological Pathology , Medical Imaging , Multiparametric Mri , Transrectal Ultrasound , Targeted Biopsy , லாரன்ஸ் கிலோட்ஜ , சர்வதேச சமூகம் ஆஃப் சிறுநீரக நோயியல் , சன்னிபிரூக் ஆரோக்கியம் அறிவியல் மையம் , மருத்துவ ரீதியாக முக்கியமான நோய் , மதிப்பீடு ப்ரொஸீஜர்ஸ் , சர்வதேச சமூகம் , சிறுநீரக நோயியல் , மருத்துவ இமேஜிங் , இலக்கு பயாப்ஸி ,