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MRI-targeted biopsy shows value in prostate cancer


February 5, 2021 Multiparametric MRI-targeted biopsy for clinically significant prostate cancer can yield detection rates similar to systematic transrectal ultrasound-guided (TRUS) biopsy, while potentially enabling over one-third of prostate biopsies to be avoided, according to research published online February 4 in
In a multicenter, prospective, and randomized phase III study called PRostate Evaluation for Clinically Important Disease: MRI vs. Standard Evaluation Procedures (PRECISE), a team of researchers from Canada found that providing targeted biopsies after a positive multiparametric MRI scan was noninferior to systematic TRUS biopsies for detecting prostate cancers with an International Society of Urological Pathology grade group (GG) of 2 or higher. ....

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Is This Really Cancer?


In prostate cancer, as in life, you roll the dice.
In craps, 3+3 is called a hard six. It s hard because you can only win if you repeat with a combination of 3+3. Any other sixes you roll 4+2, 5+1 are losers.
Gleason 3+3 is a hard six in prostate cancer. It is the lowest grade cancer in the traditional Gleason scoring system. Still, to the eye of a pathologist, a Gleason 6 looks like a malignancy.
Now, a few experts are questioning whether this hard six is a cancer at all. Some urologists see a Gleason 6 as a noncancerous growth that has the potential to be invasive, but most likely will never spread to other organs or end up killing a man. ....

United States , Scott Eggener , Laurence Klotz , Edward Uthman , Jonathan Epstein , Georged Lundberg , Bert Vorstman , Johns Hopkins , William Catalona , Peter Carroll , University Of Texas Mcgovern Medical School , University Of Chicago , International Society Of Urological Pathology , University Of California San Francisco , Grade Group , Texas Society Of Pathologists , Northwestern University , California San Francisco , International Society , Urological Pathology , Texas Society , Texas Mcgovern Medical School , Disorder Of Skin , Eruption Of Skin , Neoplastic Disease , Basal Cell Carcinoma ,