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Substantial transmission, dr. fauci says booster shots, maybe. listen. >> we are assuming that sooner or later we're going to have to give boosters. i would hope that the degree of elevation of response that we will see with the boost might actually give us a lot of wiggle room of not necessarily needing a boost often. but as you say, we are humble, and we are modest about it. we don't know the answer to that. >> when will wite know the answ to that? how long does it take, how big of a sample, and how much of a calendar to know are we going to need a third shot, are we good or are we going to ...

Is not a decision officials took lightly. joining us now the director of vaccine, and the attending physician in the division of infectious diseases at children's hospital of philadelphia, dr. paul offett. i would like to start with, can you explain mask wearing guidance and the potential for vaccine mandates? i guess the big question is what is the danger of the delta variant continuing to go through the country. why must we prevent it? >> right. well, delta variant is far more contagious tan the first two variants that came into the country. the d 614 g, swept through europe, asian, swept ...