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Genetics and Genetic Testing to Inform Myelofibrosis Clinical Management

Genetics already informs prognosis, may help guide therapy development beyond JAK2 inhibition ....

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Monitoring Myelofibrosis Treatment Response: Guidelines and Considerations

Aaron Gerds, MD, MS, reviews the National Comprehensive Cancer Network (NCCN) guidelines for monitoring myelofibrosis treatment response and delves into crucial aspects like patient impressions, physical examinations, and symptoms. ....

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Integrating Momelotinib: NCCN Guidelines and Drug Comparison

Aaron Gerds, MD, MS, explores the FDA approval of momelotinib and its swift integration into National Comprehensive Cancer Network (NCCN) guidelines. He reviews different JAK inhibitors based on adverse effects and treatment goals, addressing potential treatment-related anemia in myelofibrosis. ....

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Prognosis and Treatment Strategies in Myelofibrosis: Risk Assessment and Therapeutic Goals

Aaron Gerds, MD, MS, explores myelofibrosis risk assessment, treatment goals, and therapeutic strategies, including JAK (Janus kinase inhibitors) inhibitors and transplant considerations. ....

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Understanding Myelofibrosis: Disease Spectrum and Impact on Quality of Life

Aaron Gerds, MD, MS, compares myelofibrosis with other myeloproliferative neoplasms, explores its prevalence in the US, and reviews the diverse clinical presentations and the impact on patients’ quality of life. ....

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