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The Tigers gained 422 yards in a 28-7 loss at Duke, but turned the ball over twice in the red zone and saw another second-half drive ended when quarterback Cade Klubnik slid a yard ahead of the first-down line. KEY MATCHUP Clemson QB Cade Klubnik vs. Charleston Southern defense. Most eyes at Memorial Stadium will be on Klubnik, who couldn't generate points as he began his first full season as starter.

Duke gets a short turnaround from its Labor Day takedown of preseason Atlantic Coast Conference favorite Clemson when it hosts Lafayette, a Championship Subdivision opponent from the Patriot League. Leonard blossomed last season then had a big game in leading the Blue Devils past Clemson, notably with a highlight-reel touchdown run and the ability to move the ball on the ground or through the air.

Boston College needs to beat the lone FCS team on its schedule if it has any hope of returning to bowl eligibility in its 125th season of football. The Eagles have already lost one game outside the Power 5, falling 27-24 in overtime to Northern Illinois in the opener. Holy Cross is No. 5 in FCS and looking for its 19th straight regular-season win.

Tar Heels athletic director says NCAA Committee on Legislative Relief to decide on Tez Walker eligibilty case.

NC Gov. Cooper said fans are “concerned about the fight over corporate profits threatening valued traditions like the return of football season.”