Page 35 - Ace2 News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Cannabinoid receptor agonist shows potential protective effect on SARS-CoV-2-infected human heart cells As scientists continue to search for effective antidotes to direct and indirect damage caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv* server demonstrates the potential of cannabinoid receptor agonists to alleviate myocardial damage in this condition even in the absence of any inhibitory effect on viral infection as such. The features of SARS-CoV-2 infection The SARS-CoV-2 virus appears to be a primarily...

Fool the novel coronavirus once and it can't cause infection of cells, new research suggests.

Could laser-facilitated epicutaneous vaccination for SARS-CoV-2 be an alternative to intramuscular injection? Common immunization routes for coronavirus disease 2019 (COVID-19) vaccine candidates range from intramuscular, nasal and oral to intradermal. Now, scientists at the University of Salzburg and Pantec Biosolutions AG have developed a laser-facilitated epicutaneous immunization against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. The model has induced angiotensin-converting enzyme 2 (ACE2) blocking antibodies in mice. The study, published on the pre-pr...

Proteases modulate SARS-CoV-2 spike protein activation and deactivation Proteases are enzymes that catalyze the break-down of proteins by hydrolysis and are key to the infection process of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The spike protein that initially interacts with the ACE2 receptor on the surface of host cells must undergo cleavage to initiate a conformational change that allows entry into the cell. Proteolysis can be facilitated, and has been identified to take place, at several stages: by membrane-bound proteases belonging to the host cell, such as TMPR...

Gold nanoparticles investigated as part of in vitro tool for SARS-CoV-2 drug screening Scientists have measured the interaction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein with nano-gold colloids. These nanoparticles functionalized with the S protein have different spectroscopic signals allowing for new information about the protein to be extracted. The on-going pandemic COVID-19 (coronavirus disease 2019), caused by the SARS-CoV-2, has caused over 111 million confirmed infections and 2.46 million deaths worldwide. To control and stop the SARS-CoV-2 i...