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With nearly 5 million deaths linked to antibiotic resistance globally every year, new ways to combat resistant bacterial strains are urgently needed.
Researchers have used advanced sequencing technology to determine how the mix of microbes present in patients with healthy eyes differs from the mix found in patients with dry eye.
Scientists in Switzerland have announced the discovery of a new class of antibiotics that have shown to be effective against a deadly, drug-resistant bacteria.
The relatively large molecule clogs a transport system, leading to lethal toxicity.
Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.