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A potent antibiotic emerges in the battle against deadly superbugs

Under a microscope, this drug-resistant superbug looks as benign as a handful of pebbles. Yet carbapenem-resistant Acinetobacter baumannii, or CRAB, is a nightmare for hospitals worldwide, as it kills roughly half of all patients who acquire it. Identified as a top-priority pathogen by both the World Health Organization and the U.S. Centers for Disease Control and Prevention, CRAB is the most common form of a group of bacteria that are resistant to nearly all available antibiotics. Victims are t

Switzerland , Swiss , Oladelea-ogunseitan , Paulj-hergenrother , Michael-lobritz , Kenneth-bradley , University-of-illinois , Harvard-university , Us-centers-for-disease , World-health-organization , Drug-administration , Disease-control

Scientists discover new antibiotic that can eliminate killer bacteria

Scientists from Harvard University and Roche discovered a new way of targeting multi-drug resistant pathogen.

Bacteria , Ntibiotic- , Acinetobacter-baumannii , World-health-organisation- , Zosurabalpin , Roche , R-michael-lobritz ,

BBC News

powerful antibiotics, posing a major threat to human health. the new antibiotic, zosurabalpin, defeated one of the toughest of all superbugs. it's called carbapenem—resista nt acinetobacter baumannii, or crab for short. it's one of the three most critical drug—resistant pathogens, according to the world health organization, because it's so hard to kill. crab thrives in hospitals, where it preys on patients with already weakened immune systems. it's resistant to nearly all antibiotics and has a mortality rate of around 50%. archive: a life-saving drug which has revolutionised - medical science. since the discovery of the first antibiotic — penicillin — these precious drugs have saved countless lives. but there's been no new class of antibiotics against the most resistant bacteria, known as "gram—negative", in over 50 years.

One , Threat , Crab , Antibiotics , Antibiotic , Superbugs , Human-health , Acinetobacter-baumannii , Toughest , Carbapenem-resista , Zosurabalpin , Patients

New antibiotic zosurabalpin shows promise against superbug

Researchers report that a new type of antibiotic has proved its mettle against a deadly superbug.

United-states , Kenneth-bradley , Michael-lobritz , University-of-pennsylvania , Harvard-university , Early-development , Us-centers-for-disease , Roche-pharma-research , Cnn , Disease-control , Hoffmann-la-roche , Resistance-threats

Old-fashioned screening approach yields new antibiotic class

Researchers have identified a new class of antibiotics that works by blocking the transportation of lipopolysaccharide (LPS) to the outer membrane of the gram-negative bacterium Acinetobacter baumannii. The most advanced member of the class, zosurabalpin (RG-6006, Roche AG), was effective against multiple A. baumannii strains, including carbapenem-resistant and multidrug-resistant strains.

Acinetobacter-baumannii , Gram-negative , Harvard-medical-school , Roche-ag ,

BBC News at Six

BBC News at Six
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Infections , Antibiotics , Medicine , Research , Field , Health-care , One , Antibiotic , Superbugs , Toughest , Zosurabalpin , Patients

BBC News at One

joining me now is our medical editor, fergus walsh. how excited should we be by this? this is promising and a bit of good news. research published in the journal nature, its over 50 years since we had a new class of antibiotic against this type of bacterium. the book in question is resistant, acinetobacter baumannii, or crab for short. crab thrives in hospitals where patients are already immune suppressed. they may have blood infections, be in intensive care, and it has a mortality rate of around 50% because there are so few drugs to treat it. now, this particular antibiotic in trials in the labs and in mice, it killed the bacterium. now, in humans, we are a long way off from having a new one that we can use in hospitals, it

Research , Fergus-walsh , Bit , News , Journal-nature , 50 , Question , Class , Antibiotic , Bacterium , Type , Acinetobacter-baumannii

BBC News at Ten

picture, whether or not people feel better or worse off this year, he will be hoping that something comes along to help him out from behind in the polls, so take today is a strong hint but no guarantee of what's likely to happen but i all right, hannah miller, thank you, at westminster. scientists have welcomed the discovery of a new type of antibiotic, raising hopes it could control one of the most dangerous superbugs. the new drug is still at the experimental stage, but if human trials work out, it would be the first new treatment against this type of bacteria in more than half a century. fergus walsh has that story. bacteria are constantly evolving and some are now able to resist even the most powerful antibiotics, posing a major threat to human health. the new antibiotic, zosurabalpin, defeated one of the toughest of all superbugs. it's called carbapenem—resistant acinetobacter baumannii, or crab for short.

People , Something , Hannah-miller , Hint , Guarantee , Picture , Polls , Behind , At-westminster , One , Drug , Antibiotic

The Context

it's called carbapenem—resistant acinetobacter baumannii — or crab for short. it's one of the three most critical drug—resistant pathogens according to the world health organization because it's so hard to kill. crab thrives in hospitals where it preys on patients with already weakened immune systems. it is resistant to nearly all antibiotics and has a mortality rate of around 50%. a life—saving drug that has - revolutionized medical science. since the discovery of the first antibiotic, penicillin, these precious drugs have saved countless lives. but there's been no new class of antibiotics against the most resistant bacteria, known as "gram—negative", in over 50 years. research in the journal nature explains the new compound was able to eradicate crab infections in petri dishes and in mice. but getting any new antibiotic from the lab to patients could take up

Crab , Acinetobacter-baumannii , Pathogens , World-health-organization , Three , One , Antibiotics , Patients , Life-saving-drug , Hospitals , Immune-systems , Mortality-rate

A potent antibiotic has emerged in the battle against deadly, drug-resistant superbugs

For the first time in half a century, researchers have identified a new antibiotic that appears to kill a deadly, drug-resistant superbug.

Irvine , California , United-states , Switzerland , Los-angeles , Swiss , Paulj-hergenrother , Oladelea-ogunseitan , Michael-lobritz , Kenneth-bradley , University-of-illinois , Harvard-university