Omalizumab Ups Allergenic Food Tolerance in Children With Multiple Food Allergies
Omalizumab increased the reaction threshold for peanut and other common food allergens in children with multiple food allergies.
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Omalizumab increased the reaction threshold for peanut and other common food allergens in children with multiple food allergies.
A study in The New England Journal of Medicine shows omalizumab increases allergen tolerance in individuals with multiple food allergies, offering a promising standalone treatment option.
The data follow the FDA approval of omalizumab for the reduction of allergic reactions, including anaphylaxis, that can occur after exposure to 1 or more foods.
Omalizumab, the only FDA-approved treatment for multiple food allergies, demonstrated significant efficacy in the OUtMATCH trial, with 67% achieving the primary outcome compared to 7% in the placebo group.
Detailed results from the NIH-sponsored Phase III OUtMATCH study showed treatment with Xolair increased the amount of peanuts, tree nuts, egg, milk and...