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HIV treatment linked to reduced risk for dry AMD


HIV treatment linked to reduced risk for dry AMD
Disclosures:
Ambati reports being a co-founder of iVeena Holdings, iVeena Delivery Systems, Inflammasome Therapeutics and DiceRx; has been a consultant for Allergan, Biogen, Boehringer-Ingelheim, Immunovant, Janssen, Olix Pharmaceuticals, Retinal Solutions and Saksin LifeSciences unrelated to this work; and is named as an inventor on patent applications on AMD filed by the University of Virginia or the University of Kentucky. Please see the full study for all other authors’ relevant financial disclosures.
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Jayakrishna Ambati , Proceedings Of The National Academy Sciences , University Of Virginia Center , National Academy , Advanced Vision Science , Inflammasome Therapeutics , Sciences Provides Human Data Confirming Potential , Proprietary Compounds , ஜெயகிருஷ்ணா அம்பதி , பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா மையம் , தேசிய கலைக்கழகம் , ப்ரொப்ரைடரீ கலவைகள் ,

Common HIV drugs may prevent macular degeneration, a major cause of vision loss


Study Finds
Common HIV drugs may prevent macular degeneration, a major cause of vision loss
CHARLOTTESVILLE, Va. Sometimes solutions come from the most unexpected of sources. Researchers at the University of Virginia report a common drug usually used to treat HIV may be able to help stop one of the leading causes of blindness around the globe. Scientists uncovered the connection thanks to a major discovery which calls into question modern science’s fundamental beliefs regarding DNA.
Medical professionals call these drugs Nucleoside Reverse Transcriptase Inhibitors (NRTIs) and researchers believe they can help treat dry macular degeneration, a very common cause of blindness. These results are especially puzzling considering the fact that dry macular degeneration isn’t caused by a virus like HIV. ....

Jayakrishna Ambati , University Of Virginia , Nucleoside Reverse Transcriptase Inhibitors , Advanced Vision Science , ஜெயகிருஷ்ணா அம்பதி , பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா ,

New hope for a treatment to prevent dry macular degeneration


New hope for a treatment to prevent dry macular degeneration
New hope for a treatment to prevent dry macular degeneration
By Rachel Hirschheimer | February 2, 2021 at 2:05 PM EST - Updated February 3 at 9:47 AM
CHARLOTTESVILLE, Va. (WVIR) - There’s new hope for people suffering from vision loss or dry macular degeneration thanks to drugs used to treat HIV.
“This is a huge unmet medical need. There are no approved treatments for dry macular degeneration in America or anywhere. We desperately need treatments for all these people who are potentially going blind from this disease,” Dr. Jayakrishna Ambati, professor of ophthalmology and director of the Center for Advanced Vision Science at the University of Virginia, said. ....

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HIV Drugs May Be Repurposed for Blindness


HIV Drugs May Be Repurposed for Blindness
Abstract Security Iris or Retina Scanner being used on an Intense Blue Human Eye, Macro
February 2, 2021
Blindness due to age-related dry macular degeneration (AMD) robs over 200 million people worldwide of being able to do the simplest tasks they used to take for granted, such as driving or playing with their grandkids. Currently, there is no approved treatment for AMD.
A group of drugs used to treat HIV that block DNA synthesis in the cytoplasm can be repurposed to treat an advanced form of AMD called geographic atrophy (GA), a new study suggests. The findings were published in the journal, ....

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