[Full text] Aspirin as an antifungal-lock agent in surgical catheters
p 0.001) was required to eradicate the C. albicans biofilm (Figure 1A) whereas biofilm of all the other Candida species was eradicated after 24 hours by aspirin at a concentration of 40 mg/mL ( p 0.001) (Figure 1B–D). This suggested that aspirin at a concentration of 40 mg/mL locked for 24 hours could be used as the antifungal agent in Candida related CRI. In Ko’s et al study, five days were required to eradicate the biofilm using amphotericin B and caspofungin as opposed to one day in the current study. 19 The use of aspirin therefore may have the advantages of reducing the risk o...