Improving the transparency and reliability of observational studies through registration
Florian Naudet and colleagues argue that routine registration of observational research is needed and suggest how current processes can be adapted to facilitate it From the use of booster doses against covid-191 to approval of novel cancer therapies,2 health authorities and health technology assessment bodies are increasingly relying on non-randomised trials and observational studies. The methodological problems of observational studies, such as residual confounding,3 are difficult to resolve, but concerns about transparency and reliability can be reduced through registration. Registration is ...
Source: bmj.com
