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Researchers identify six “words” used by specific immune cells to call up immune defense genes UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes -- an important step toward understanding the language the body uses to marshal responses to threats. In addition, they discovered that the incorrect use of two of these words can activate the wrong genes, resulting in the autoimmune disease known as Sjögren's syndrome. The research, conducted in mice, is published this week in the peer-reviewed journal Immunity (Cell Press). Cells h...

May 13, 2021 UCLA In the News lists selected mentions of UCLA in the world’s news media. Some articles may require registration or a subscription to view. See more UCLA In the News. Dov Waxman, professor of Israel studies at UCLA and author of several books about the conflict, said there were early and clear signs that Israelis and Palestinians were headed to calamity. “What [Biden] wanted to do was signal this was not a priority and move slowly and cautiously while dealing with a complicated domestic agenda,” Waxman said. “The problem is the Middle East always intrudes into the ag...

  In this image from a microscopy video, scientists "listen" to macrophages as they responded to an immune threat. Credit: Brooks Taylor/ UCLA Life Sciences Read Time: UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes -- an important step toward understanding the language the body uses to marshal responses to threats. In addition, they discovered that the incorrect use of two of these words can activate the wrong genes, resulting in the autoimmune disease known as Sjögren's syndrome. The research, conducted in mice, is publis...

© Brooks Taylor/UCLA In this image from a microscopy video, scientists “listen” to macrophages as they responded to an immune threat. UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes — an important step toward understanding the language the body uses to marshal responses to threats. In addition, they discovered that the incorrect use of two of these words can activate the wrong genes, resulting in the autoimmune disease known as Sjögren's syndrome. The research, conducted in mice, is published this week in the peer-review...

The advance, researchers say, is like the cellular equivalent of discovering the Rosetta stone and may eventually lead to new treatments for diseases.