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New strategy to grow and measure how tumor organoids respond to therapy

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers. ....

United States , Los Angeles , Paul Boutros , Nasrin Tavanaie , Chuyen Nguyen , Sara Sartini , Alfredo Gonzalez , Thang Nguyen , Peyton Tebon , Brandon Tsai , Bowen Wang , Michael Teitell , Ardalan Davarifar , Eugenev Cota Robles , Alexander Markowitz , Danielle Ellis , Department Of Orthopaedic Surgery , National Institutes Of Health , David Geffen School Of Medicine , Department Of Defense , Jonsson Comprehensive Cancer Center , Office Of Scientific Research , Nature Communications , Los Angeles Health Sciences , University Of California , National Science Foundation Graduate Research Fellowship ,

Fine-tuning 3D lab-grown mini tumors to help

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers. ....

Michael Teitell , Alice Soragni , Ardalan Davarifar , Paul Boutros , Thang Nguyen , Alexander Markowitz , Brandon Tsai , Sara Sartini , Chuyen Nguyen , Nasrin Tavanaie , Eugenev Cota Robles , Peyton Tebon , Alfredo Gonzalez , Bowen Wang , Jonsson Comprehensive Cancer Center , Nature Communications , David Geffen School Of Medicine , National Institutes Of Health , Office Of Scientific Research , National Science Foundation Graduate Research Fellowship , Department Of Defense , Comprehensive Cancer Center , Orthopaedic Surgery , David Geffen School , Comprehensive Cancer , National Institutes ,