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The hepatitis E virus protein ORF1 contains a region that scientists have struggled to characterize, making the structure and function of this region the subject of much debate. Now, Princeton scientists show that this region of the protein does not behave as a protease, as has been previously suggested, but instead serves as a molecular scaffold to stabilize the rest of the ORF1 protein.

Princeton scientists have revealed some of the unknown ways that COVID infects the human lung, using a new technology that shines a light (literally) on the actions of spike proteins.

/PRNewswire/ -- The National Institute of Allergy and Infectious Disease (NIAID) awarded a $6.9 million grant to researchers at the Institute for Bioscience...

Amy Banner, pictured with Ardian Banner, performs at the ceremony. The Jewish Center of Princeton held a memorial ceremony on Sunday to remember the 1.5 million children who died in the Holocaust. People gathered outside of the center, where more than 250 daffodil bulbs had been planted last fall as part of the Daffodil project, a worldwide effort to remember the children of the Holocaust by planting 1.5 million daffodils across the globe to represent all the children who died, as well as to remember the children who are suffering from humanitarian crises taking place in the world today. Daf...

Hepatitis B Virus Uses Host’s DNA Repair Proteins to Close Circle of Infection March 11, 2021 Share To establish chronic disease, the hepatitis B virus (HBV) must have its genome of relaxed circular DNA (rcDNA) turned into covalently closed circular DNA (cccDNA). Exactly how rcDNA becomes cccDNA has been unclear, but new details about the transformation have been uncovered by Princeton University researchers. According to the Princeton team, the rcDNA genome, which contains four lesions, undergoes repair by five host proteins. The new findings appeared March 11 in Nature Communications,...