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Using organoids to model early development, researchers used an emerging microscopy technology to see that new neurons struggled to reach their developmental destination in Rett syndrome lab models.
With organoids to model initial development, scientists employed a developing microscopy technology to observe that new neurons struggled to attain their developmental goal.
Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge.