Parkinson's disease risk and severity is tied to a channel in cells' 'recycling centers
E-Mail Many genetic mutations have been found to be associated with a person's risk of developing Parkinson's disease. Yet for most of these variants, the mechanism through which they act remains unclear. Now a new study in Nature led by a team from the University of Pennsylvania has revealed how two different variations--one that increases disease risk and leads to more severe disease in people who develop Parkinson's and another that reduces risk--manifest in the body. The work, led by Dejian Ren, a professor in the School of Arts & Sciences' Department of Biology, showed that the varia...
Source: eurekalert.org