'It's hugely complex': the scientists working to defeat Parkinson's | Science
Research into dopamine-producing cells and rogue proteins among efforts to find far-reaching treatment
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Research into dopamine-producing cells and rogue proteins among efforts to find far-reaching treatment
The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed.
E-Mail Many genetic mutations have been found to be associated with a person's risk of developing Parkinson's disease. Yet for most of these variants, the mechanism through which they act remains unclear. Now a new study in Nature led by a team from the University of Pennsylvania has revealed how two different variations--one that increases disease risk and leads to more severe disease in people who develop Parkinson's and another that reduces risk--manifest in the body. The work, led by Dejian Ren, a professor in the School of Arts & Sciences' Department of Biology, showed that the varia...