Molecular Switch Identified That Flips from Self-Renewal to Specialization in the Making of a Kidney
Molecular Switch Identified That Flips from Self-Renewal to Specialization in the Making of a Kidney April 5, 2021 Share Self-renewal and specialization are two opposing functions in progenitor cells. Scientists resolve the mechanisms behind the opposing developmental actions of beta-catenin, a co-activator of the established molecular Wnt signaling pathway, that paradoxically regulates both self-renewal and specialization of mammalian progenitor cells destined to become kidney cells. The new study led by Andrew McMohan, PhD, chair of the department of stem cell biology and regenerative medic...
Source: genengnews.com