A crossover of artworks | Maribyrnong & Hobsons Bay
A new exhibition exploring colour in the face of a pandemic is showing at Five Walls art gallery in Footscray. […]
Source: starweekly.com.au
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Entrectinib Impresses in Certain Lung Cancers
Crizotinib (Xalkori) has approval as first-line therapy for ROS1 fusion-positive metastatic NSCLC but has poor CNS penetration, the authors noted, adding that in about half of patients treated with crizotinib, initial progression occurs only in the CNS. Entrectinib is designed to cross the blood-brain barrier, and preclinical studies showed that the agent achieves high CNS concentrations, which were associated with strong efficacy in brain-tumor models. Integrated Analysis For the analysis, the investigators evaluated entrectinib in three phase I or II clinical trials of patients with locall...
Source: medpagetoday.com