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Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model
A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The
Journal of Nuclear Medicine. The results of the murine study indicate that radionuclide therapy promotes prostate cancer immunogenicity, provoking a cellular response that makes the tumors more receptive to immunotherapy.
Prostate cancer is generally viewed as an immunological cold cancer in which immunotherapies only have moderate success. Increasing prostate cancer immunogenicity with prostate-specific membrane antigen (PSMA) radionuclide therapy, however, might render immunotherapies more successful. In our research we sought to exploit this effect by combining radionuclide therapy with immunotherapy in a mouse model of prostate cancer. ....

United States , University Of California Los Angeles , Emily Henderson , Journal Of Nuclear Medicine , Assistant Professor , Preclinical Theranostics , California Los Angeles , Prostate Cancer , Molecular Imaging , Mouse Model , Nuclear Medicine , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா லாஸ் ஏஞ்சல்ஸ் , எமிலி ஹென்டர்சன் , இதழ் ஆஃப் அணு மருந்து , உதவியாளர் ப்ரொஃபெஸர் , கலிஃபோர்னியா லாஸ் ஏஞ்சல்ஸ் , நோயெதிர்ப்பு சிகிச்சை , ப்ராஸ்டேட் புற்றுநோய் , மூலக்கூறு இமேஜிங் , சுட்டி மாதிரி , அணு மருந்து ,

Georgia reports 3,000-plus virus cases Sunday

ATLANTA – Georgia reported more than 3,000 new COVID-19 cases Sunday, according to the Georgia Department of Public Health. ....

United States , Georgia Department Of Public Health , Georgia Department , ஒன்றுபட்டது மாநிலங்களில் , ஜார்ஜியா துறை ஆஃப் பொது ஆரோக்கியம் , ஜார்ஜியா துறை , உயிர் வேதியியல் ,

Highly Reactive Rubella Spike Ectodomain (E1-E2) Antigen Launched

Feb 08 2021 Read 513 Times
Aalto Bio Reagents is pleased to announce the availability of the first highly reactive recombinant Rubella Spike Ectodomain (E1-E2) antigen, code BM 6428, which has shown exceptional detection of both IgG and IgM antibodies in ELISA and bead-based immunoassays. Purified from recombinant expression in insect cells, this high-quality antigen has guaranteed lot to lot consistency and considerably shorter lead times for large lots compared to native antigen production. Using the protein sequence from the Rubella vaccine strain HPV-77, Aalto Bio Reagents was able to produce a very reliable product, ready for use in the development of highly specific IgG and IgM assays. ....

Aalto Bio Reagents , Rubella Spike Ectodomain , Philip Noone , ஆல்டோ உயிர் ரீயேஜெஂட்ஸ் , பிலிப் யாரும் இல்லை ,

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

A team of researchers recently examined the SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia. ....

Liji Thomas , Coronavirus Disease Covid 19 , Sars Cov 2 , Angiotensin Converting Enzyme 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , சர்வதேச பரவல் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

Novel immunotherapy approach to revert the main hallmarks of cat allergy

Novel immunotherapy approach to revert the main hallmarks of cat allergy
Researchers from the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) brought forward the potential of high doses of a specific adjuvant molecule, namely CpG oligonucleotide, in successfully modulating the immune system s allergic response to the main cat allergen Fel d 1, thereby inducing a tolerance-promoting reaction and reverting the main hallmarks of cat allergy.
The researchers analyzed the molecular mechanisms underlying this tolerance and proposed a pre-clinical allergen-specific immunotherapy approach to improve the treatment and control of this common type of allergy. The full study results were published recently in the renowned international journal ....

Markus Ollert , Emily Henderson , Department Of Infection , Immunity Of The Luxembourg Institute Health , European Academy Of Allergy , Luxembourg Institute , European Academy , Clinical Immunology , Natural Killer , Tumour Necrosis Factor , Senior Lead , Cat Allergy , Anti Inflammatory , Immune Response , Immune System , எமிலி ஹென்டர்சன் , துறை ஆஃப் தொற்று , நோய் எதிர்ப்பு சக்தி ஆஃப் தி லக்ஸம்பர்க் நிறுவனம் ஆரோக்கியம் , ஐரோப்பிய கலைக்கழகம் ஆஃப் ஒவ்வாமை , லக்ஸம்பர்க் நிறுவனம் , ஐரோப்பிய கலைக்கழகம் , மருத்துவ நோயெதிர்ப்பு , இயற்கை கில்லர் , மூத்தவர் வழி நடத்து , பூனை ஒவ்வாமை , நோயெதிர்ப்பு சிகிச்சை ,