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Matching, they should give some guidance on which combinations make sense and when. if i got the johnson & johnson dose and research shows that moderna and pfizer s boosters might be stronger, why would anyone opt for the johnson & johnson booster? i think there s not a lot of reason to. if you look at there was one group of original folks who got the single dose j&j who had this increased risk of a rare cerebral venus thrombosis, important side effect, which makes one wonder whether anyone should get the second dose, particularly if you are a woman under the age of 50, which seem to be the highest risk group. and when you look at the data for the j&j boost, yeah, a second dose of j&j can increase the neutralizing antibodies by fourfold. but the moderna boost increased it by over 70fold. and pfizer about 35-fold. ....