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but a booster with pfizer sent those antibodies up 35 fold. and with a moderna boost, they jumped 76 fold. still, no idence yet that mixing leads to greater long in chicago, nathan bean got the j&j one-shot and experienced a breakthrough infection four months later. >> night two of coronavirus. >> reporter: after talking with getting a moderna boos precaution before seeing his mother, who is immunocompromised. >> i was excited to be able to get this moderna shot. we're going to be able to celebrate christmas and just celebrate being with each other for the first time in 2 1/2 years. >> whit johnson back with us here tonight, and whit, with the sign-o the cdc director, then how soon could we see these boosters roll out across the country? >> reporter: david, some people will be able to go out and get these booster shots as early as tomorrow at pharmacies, vaccinatn dss the country. the white house insists there is
matching, they should give some guidance on which combinations make sense and when. >> if i got the johnson & johnson dose and research shows that moderna and pfizer's boosters might be stronger, why would anyone opt for the johnson & johnson booster? >> i think there's not a lot of reason to. if you look at -- there was one group of original folks who got the single dose j&j who had this increased risk of a rare cerebral venus thrombosis, important side effect, which makes one wonder whether anyone should get the second dose, particularly if you are a woman under the age of 50, which seem to be the highest risk group. and when you look at the data for the j&j boost, yeah, a second dose of j&j can increase the neutralizing antibodies by fourfold. but the moderna boost increased it by over 70fold. and pfizer about 35-fold.
brookings institution. we are just days away from a full fda authorization when it comes to johnson & johnson boosters and moderna -- eua, i should say. how soon could those shots be in arms for folks? >> yeah, they could be ready as soon as probably after the cdc committee meets, which is next thursday. so, remember, the sequence, the fda gives its emergency use authorization language, the cdc, which is meeting next thursday on covid vaccines, picks that up, and then gives further guidance, and it's -- that's where kind of the details come for what to do, what not to do for physicians such as myself. so, you could see something literally, yasmin, the next day. now, remember, the moderna boost is half the dose of doses one and two. the pfizer boost is exactly the same as one and two. and then the johnson & johnson boost is exactly the same as the first dose. so you could imagine that, you know, friday, j&j recipients, which is anyone over the age of 18, and so let me emphasize. it's confusing because it's not
this is a group with lower overall efficacy than we have seen with the mrna vaccines, so there is some urgency here. >> reporter: the advisers also launching into a spirited debate over whether j&j should have been a two-dose vaccine to begin with. the company defending the need for a single-shot option in a pandemic. and today, a key question on mixing and matching vaccines, specifically whether it's safe and effective to boost johnson & johnson with an mrna shot. a small study shows that a johnson & johnson booster dose triggered a climb in antibody levels fourfold, but a booster with pfizer sent those up 35-fold. and with a moderna boost, they jumped 76-fold. no decision today, but the panel members acknowledging the public needs guidance soon. >> in the real world all these combinations of boosters are already happening. we can't hide from it, and i do think we need to give guidance to the public. >> whit johnson back with us tonight.