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Covid and beyond

Not surprisingly, COVID-19 vaccines and antiviral treatments dominated headlines in 2021. But in addition to these breakthroughs, pharmaceutical and ....

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Year in pharma: COVID-19 and beyond - American Chemical Society

Year in pharma: COVID-19 and beyond - American Chemical Society
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Creating a needle-free COVID-19 vaccine


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Vaccines are mostly synonymous with needles, an efficient and effective way to provide immunity to myriad infections. As COVID-19 vaccination efforts roll out across the U.S. and the world, some experts believe that a vaccine administered through the nose could be just as effective and easier to administer. A cover story in
Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, explains the pros and cons of nasal vaccines.
SARS-CoV-2, the virus that causes COVID-19, often enters the body through the nose when a person inhales. From there it encounters a network of mucosal membranes that form the body s first line of immune defense, writes Associate Editor Ryan Cross. The cells of mucus membranes create a special type of antibody, which experts say can provide both mucosal and systemic immunity when triggered by a vaccine that is sprayed into the nasal cavity. In contrast, injectable vaccines only trigger a systemic immune respo ....

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Making stem cell transplants safer and more effective


Making stem cell transplants safer and more effective
For cancer patients, the use of hematopoietic stem cell transplants can be a game changer in terms of treatment and recovery. However, most people need to undergo a combination of chemotherapy and radiation before transplants become an option. A new article in
Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, sheds light on progress toward making stem cell transplants safer and more effective.
Chemotherapy and radiation are used as a prelude to stem cell transplants in a process known as conditioning, writes Associate Editor Ryan Cross. This allows doctors to clear out diseased cells in the body and make room for healthy ones, but conditioning can be very harsh; it also kills healthy cells and can cause significant side effects, making recovery that much harder. Therefore, stem cell transplants are often under-used. Researchers and drug companies are now working to develop new t ....

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