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Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma: RATIONALE-305 randomised, double blind, phase 3 trial

Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma: RATIONALE-305 randomised, double blind, phase 3 trial
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United States , Eteläuomen Läi , South Korea , Jin Wang , Genentechf Hoffmann , Asher Biotherapeutics , Daiichi Sankyo , Chipscreen Biosciences , Bristol Myers Squibb , Ashfield Medcomms , Merck Biopharm , Merck Serono , Samsung Bioepis , Lyell Immunopharma , Calithera Biosciences , Eli Lilly , Keymed Biosience , Astellas Pharma , Asiav Europe , Dewan Zang , Merck Biopharma , Aeglea Biotherapeutics , Hutchinson Medipharma Incyte , Lynda Mcevoy , Pierre Fabre , Simon Lancaster ,

Adagrasib, Cetuximab May Benefit KRASG12c Colorectal Cancer Patients

Adagrasib, Cetuximab May Benefit KRASG12c Colorectal Cancer Patients
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United States , Redx Pharma , Daiichi Sankyo , Bristol Myers Squibb Medarex , Genentech Roche , Eli Lilly , Scott Kopetz , Navire Pharma , Astrazeneca Medimmune , Lutris Pharma , University Of Texas Md Anderson Cancer Center , Harbinger Health , Gilead Sciences , Guardant Health , American Association For Cancer Research , Serono Inc , Zentalis Pharmaceuticals , Boehringer Ingelheim , Foundation Medicine , Servier Pharmaceuticals , Xilis Inc , Iylon Precision Oncology , Bayer Health , Tachyon Therapeutics Inc , Takeda Pharmaceuticals , Jacobio Pharmaceuticals Group Co ,

Adagrasib/Cetuximab Combo Has Activity in KRAS G12C+ Locally Advanced or mCRC

Adagrasib plus cetuximab elicited a 34% objective response rate in patients with previously treated KRAS G12C-mutant advanced colorectal cancer. ....

United States , San Diego , Daiichi Sankyo , Bristol Meyers Squibb , Redx Pharma , Eli Lilly , Navire Pharma , Genentech Roche , Scott Kopetz , Astrazeneca Medimmune , Lutris Pharma , Bristol Myers Squibb Medarex , Bayer Health , Drug Administration , Iylon Precision Oncology , Gilead Sciences , University Of Texas Md Anderson Cancer Center , Serono Inc , Takeda Pharmaceuticals , Boehringer Ingelheim , Jazz Pharmaceuticals , Zentalis Pharmaceuticals , Foundation Medicine , Johnson Janssen Pharmaceuticals , Guardant Health , Jacobio Pharmaceuticals Group Co ,

Jay Bradner returns to lead R&D at Amgen—Chutes & Ladders

Jay Bradner returns to lead R&D at Amgen—Chutes & Ladders
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Rahul Kakkar , Astrazeneca Medimmune , Stephen Hoge , Chris Boshoff , Adam Rosenthal , Clay Siegall , Ruben Rodriguez , Jason Duncan , David Reese , Thomas Jensen , Don Haut , Vincent Oneill , Max Bayer , John Finn , Kathy Spencer Pike , Galvani Bioelectronics , Aamir Malik , Diane Wong , Sarah Skerratt , Arpa Garay , Edward Freedman , Fiona Marshall , Jean Jacques Bienaim , Alexander Hardy , Aiolos Bio , George Mahaffey ,

Poor oral health could lessen survival from h

An international study has revealed strong associations between oral health and survival among people diagnosed with head and neck cancer. Specifically, better oral health, as evidenced by the number of natural teeth and dental visits prior to the time of diagnosis, was associated with increased survival. ....

North Carolina , United States , Adams School , Sao Paulo , Comunidad Autonoma De Cataluna , Chapel Hill , Trevor Hackman , Antoniol Amelio , Wendellg Yarbrough , Douglasr Farquhar , Astrazeneca Medimmune , Chrisb Agala , Investigacion Cientificay Tecnologica , Andrewf Olshan , Carole Fakhry , Kimon Divaris , Jason Tasoulas , Inovio Pharmaceuticals , National Institute Of Environmental Health Sciences , Lg Chem Life Sciences Innovation Center , University Cancer Research Fund , Framework Programme , Adams School Of Dentistry , National Institute For Health Research , World Cancer Research Fund , Speaker Bureau ,