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Proof of concept for automated Fire Monkey High Molecular Weight (HMW) DNA extraction/size selection process in multi-well filter plate format validated by sequencing
Hands-free automated protocol on a bespoke Tecan Fluent 780 robotic liquid handler integrated with a Rotanda 460 robotic centrifuge
Extraction produces library-ready homogenous, long-length DNA (average 106kb) for short- and long-read DNA sequencing
Resultant sequence quality equivalent to manually-extracted DNA: >30Gb at N50 longer than 30kb
Automated DNA extraction enables further growth in high-throughput DNA sequencing applications with estimated market to >$50bn over the next 10 years
The UK genomic tools developer, RevoluGen Ltd. (RevoluGen or the Company), today announces the technology validation of the world s first automated extraction of library-ready High Molecular Weight (HMW) DNA in a multi-well filter plate format. ....

United Kingdom , Gemma Langridge , Sue Charles , Georgios Patsos , Head Corporate Communications , United Kingdom Quadram Institute , Revolugen Ltd , Merck Kga , Group Leader , Merck Kgaa , Fire Monkey High Molecular Weight , Tecan Fluent , High Molecular Weight , Automated Fire Monkey , Fire Monkey , Pieter Haitsma , Oxford Nanopore , Fire Flower , Quadram Institute , Antibiotic Microbial Resistance , Illumina Whole Genome Sequencing , Nucleic Acid Isolation , Investor Relations , ஒன்றுபட்டது கிஂக்டம் , ஜெம லாங்ரிட்ஜ் , வழக்கு சார்லஸ் ,