Softening a Hardened Heart Counts on Cardiac Splicing Regulators
Scientists have developed a therapeutic agent to treat heart failure caused by the stiffening of the walls of the chambers of the heart that prevents adequate filling of the chambers even when the pumping activity of the heart is normal. This form of heart failure has no available treatment at present. The authors have targeted a splicing factor that regulates the splicing of titin, a protein that regulates the elasticity of the heart walls.
Source: genengnews.com