Leptin puts the brakes on eating via novel neurocircuit
E-Mail Credit: Elsevier, 2021 Philadelphia, April 6, 2021 - Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain. Now, a new study in mice describes novel neurocircuitry between midbrain structures that control feeding behaviors that are under modulatory control by leptin. The study appears in John Krystal, MD, Editor of Biological Psychiatry, said of the findings, "Omrani and colleagues shed light on how, in non-obese anim...