Stay updated with breaking news from Basic Biology. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Salk scientists found that manipulating how cell's produce energy can reduce melanoma tumor growth and enhance immune response in mice. Their findings may be leveraged to create new cancer therapeutics that do not harm mitochondria and cells.
Salk scientists found that manipulating how cell's produce energy can reduce melanoma tumor growth and enhance immune response in mice. Their findings may be leveraged to create new cancer therapeutics that do not harm mitochondria and cells.
Plants orient their organs in response to the gravity vector, with roots growing towards gravity and shoots growing in the opposite direction. The movement of statoliths responding to the inclination relative to the gravity vector is employed for gravity sensing in both plants and animals. However, in plants, the statolith takes the form of a high-density organelle, known as an amyloplast, which settles toward gravity within the gravity sensing cell. Despite the significance of this gravity sensing mechanism, the exact process behind it has eluded scientists for over a century. A groundbreakin...
Helicobacter pylori cagA+ strains cause gastric inflammation, ulcers, and cancer. Previous reports have shown that the cagA gene-encoded protein “CagA” plays a crucial role in gastric carcinogenesis. However, the underlying mechanisms remain to be fully elucidated. Researchers from Japan used animal models and laboratory-cultured human gastric epithelial cells to demonstrate that CagA works by disrupting the Wnt/Planar Cell Polarity (PCP) signaling pathway.
Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA+ strains dramatically increases the risk of developing gastric cancer.