Helicobacter pylori cagA+ strains cause gastric inflammation, ulcers, and cancer. Previous reports have shown that the cagA gene-encoded protein “CagA” plays a crucial role in gastric carcinogenesis. However, the underlying mechanisms remain to be fully elucidated. Researchers from Japan used animal models and laboratory-cultured human gastric epithelial cells to demonstrate that CagA works by disrupting the Wnt/Planar Cell Polarity (PCP) signaling pathway.
New study throws light on mechanisms underlying helicobacter pylori-induced gastric cancer miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA+ strains dramatically increases the risk of developing gastric cancer.
After coming under public criticism for using Japanese Prime Minister Fumio Kishida's residence for a private party, his son Shotaro Kishida, is set to resign
After coming under public criticism for using Japanese Prime Minister Fumio Kishida's residence for a private party, his son Shotaro Kishida, is set to resign